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DIC
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DIC

CAS: 693-13-0

Ref. 3D-FD02073

1kg
559.00 €
2kg
1,013.00 €
4kg
1,721.00 €
250g
242.00 €
500g
381.00 €
Estimated delivery in United States, on Tuesday 3 Dec 2024

Product Information

Name:
DIC
Synonyms:
  • 1,3-Diisopropylcarbodiimide N,N'-Diisopropylcarbodiimide
  • (E)-dipropan-2-yldiazene
  • (Propan-2-yl)([[(propan-2-yl)imino]methylidene])amine
  • 1,3-Diisopropylcarbodiimide
  • 2-Propanamine, N,N'-methanetetraylbis-
  • Carbodiimide, diisopropyl-
  • Carbodimide, N,N'-Diisopropyl-
  • Diisopropyl-Carbodiimid
  • Diisopropylcarbodiimide
  • Dipc
  • See more synonyms
  • Dipcdi
  • Dipci
  • N,N'-Diisopropyl carbodiimide
  • N,N'-Methanetetraylbis(1-methylethylamine)
  • N,N'-Methanetetraylbis(2-propanamine)
  • N,N'-Methantetraylbis(1-methylethylamin)
  • N,N'-dipropan-2-ylcarbodiimide
  • N,N'-metanotetrailbis(1-metiletilamina)
  • N,N′-Diisopropylmethanediimine
  • Nsc 42080
  • PCI
  • N,N′-Diisopropylcarbodiimide
Description:

DIC is a carbodiimide used as a coupling reagent for amide and ester formation, widely employed in peptide synthesis in presence of additives such as HOBt or HOAt to supress racemisation. Being a liquid, DIC is easier to handle than the solid DCC and forms a DCM-soluble urea by-product, while DCC generates a urea by-product insoluble in most organic solvents. Since the presence of insoluble urea is reportedly problematic in solid-phase peptide synthesis, for this application DIC is more suitable than DCC. A possible side-reaction with DIC and carbodiimides in general is the formation of an N-acylurea, which can be limited by conducting the reaction in DCM or chloroform at low temperatures, and by adding the amine at last.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
126.2 g/mol
Formula:
C7H14N2
Purity:
Min. 99.0%
Color/Form:
Colorless Clear Liquid
InChI:
InChI=1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
InChI key:
InChIKey=BDNKZNFMNDZQMI-UHFFFAOYSA-N
SMILES:
CC(C)N=C=NC(C)C
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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