2,4-Dihydroxypyrimidine-5-carboxylic acid anhydrous

CAS: 23945-44-0

Ref. 3D-FD08255

Product Information

• Name: 2,4-Dihydroxypyrimidine-5-carboxylic acid anhydrous
• Synonyms: Uracil-5-carboxylic acidIsoorotic acidUracil 5-carboxylic acid
• Brand: Biosynth
• Description: 2,4-Dihydroxypyrimidine-5-carboxylic acid anhydrous (2,4DPA) is a metabolite of the drug 2,4-diaminopyrimidine. It inhibits protein synthesis in cells through hydrogen bonding interactions with dna duplexes and has been shown to be toxic to bacteria by inhibiting fatty acid biosynthesis. 2,4DPA is used as a standard in biological assays to measure uptake and light exposure. The analytical method for measuring 2,4DPA relies on hydrochloric acid (HCl) as a solvent that converts the material into its dimethyl ester derivative. This derivative can be quantified by gas chromatography/mass spectrometry (GCMS).

Chemical properties

• Molecular weight: 156.1 g/mol
• Formula: C₅H₄N₂O₄
• Purity: Min. 94.0 Area-%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C5H4N2O4/c8-3-2(4(9)10)1-6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
• InChI key: InChIKey=ZXYAAVBXHKCJJB-UHFFFAOYSA-N
• SMILES: O=C(O)c1c[nH]c(=O)[nH]c1=O