Di-tert-butyl chloromethyl phosphate

CAS: 229625-50-7

Ref. 3D-FD137343

Product Information

• Name: Di-tert-butyl chloromethyl phosphate
• Synonyms: Di-tert-Butyl chloromethyl phosphate Phosphoric acid di-tert-butyl chloromethyl ester
• Brand: Biosynth
• Description: Di-tert-butyl chloromethyl phosphate (DBCMP) is a phosphite that has been shown to be an effective additive for the prevention of fluorescence in cell-based assays, such as Covid-19. DBCMP is made by reacting potassium phosphate with trifluoroacetic acid and calcium carbonate. It has been used extensively in metabolic studies of cinnarizine, a drug that inhibits the activity of phosphodiesterase enzymes. DBCMP is stable in acidic conditions and can be stored at room temperature with minimal degradation. The reaction between DBCMP and nucleophiles leads to the formation of a linker, which can be cleaved by base hydrolysis or nucleophilic attack.

Chemical properties

• Molecular weight: 258.68 g/mol
• Formula: C₉H₂₀ClO₄P
• Purity: Min. 95%
• Color/Form: Colorless Clear Liquid