Dimethyl fumarate

CAS: 624-49-7

Ref. 3D-FD15538

Product Information

• Name: Dimethyl fumarate
• Synonyms: Fumaric acid dimethyl ester, (2E)-2-Butenedioic acid dimethyl ester, (E)-2-Butenedioic acid dimethyl ester, (E)-But-2-enedioic acid dimethyl ester, 2-Butenedioic acid (2E)-, 1,4-dimethyl ester, 2-Butenedioic acid (2E)-, dimethyl ester, 2-Butenedioic acid (E)-, dimethyl ester, Allomaleic acid dimethyl ester, Azl-O 211089, Bg 00012, Bg 12, Boletic acid dimethyl ester, Dimethyl (E)-2-butenedioate, Dimethyl (E)-butenedioate, Dimethyl trans-ethylenedicarboxylate, Dimethylfumarat, Dimethylfumarate, Fumarate De Dimethyle, Fumarate, Dimethyl, Fumarato De Dimetilo, Fumaric acid, dimethyl ester, Fumarsaeure-Dimethylester, Methyl fumarate, Nsc 167432, Nsc 25942, Panaclar, Skilarence, Tecfidera, Tecfira, dimethyl (2E)-but-2-enedioate, trans-1,2-Ethylenedicarboxylic acid dimethyl ester, trans-Butenedioic acid dimethyl ester

Description

Dimethyl fumarate (DMF) is a drug that acts as a prodrug for the active metabolite monomethyl fumarate (MMF). It is used in the treatment of psoriasis and other skin diseases, including erythema nodosum leprosum. DMF has been shown to significantly up-regulate the expression of proliferating cell nuclear antigen (PCNA), which is a response element for pdgf-bb. DMF also has antioxidant properties, which may be due to its ability to inhibit reactive oxygen species production. This drug also inhibits the activity of certain enzymes and blocks drug transporters that are involved in bowel disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 144.13 g/mol
• Formula: C₆H₈O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
• InChI key: InChIKey=LDCRTTXIJACKKU-ONEGZZNKSA-N
• SMILES: COC(=O)/C=C/C(=O)OC