MLi-2

CAS: 1627091-47-7

Ref. 3D-FD157083

Product Information

• Name: MLi-2
• Synonyms: rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole
• Brand: Biosynth
• Description: A brain-penetrant inhibitor of leucin-rich repeat kinase 2 (LRRK2) with IC50 = 0.76 nM and anti-parkinsonian activity. Gain-of-function mutations in LRRK2 gene lead to increased familial and idiopathic risk of developing the disease. The inhibitors of the kinase activity have therapeutic potential against Parkinson’s disease.

Chemical properties

• Molecular weight: 379.46 g/mol
• Formula: C₂₁H₂₅N₅O₂
• Purity: Min. 98 Area-%
• Color/Form: Powder