2,4-Difluorobromobenzene

CAS: 348-57-2

Ref. 3D-FD16010

Product Information

• Name: 2,4-Difluorobromobenzene
• Synonyms: 1,4-Dichloro-2-Fluorobenzene, 2,4-Difluoro-1-bromobenzene, 2,4-DifluoroBrmorobenzene, 2,4-Difluorophenyl bromide, 4-Bromo-1,3-difluorobenzene, Benzene, 1-bromo-2,4-difluoro-, 1-Bromo-2,4-difluorobenzene, 4-(Trifluoromethylthio)

Description

2,4-Difluorobromobenzene is an efficient method for synthesizing a variety of fluorinated arenes. It is a member of the class of compounds known as fluoroarenes. The synthesis starts with 2-bromobenzene, which reacts with butyllithium in the presence of trifluoroacetic acid to form 2-bromo-4-fluorobenzene. This compound can then be converted to the desired product by treatment with activated carbon or photochromic agents such as benzophenone and tetracyanoethylene. 2,4-Difluorobromobenzene can also be used as a synthetic intermediate for antifungal agents such as fluconazole and it has been shown to have some activity against Cryptococcus neoformans.

• Brand: Biosynth

Chemical properties

• Molecular weight: 192.99 g/mol
• Formula: C₆H₃BrF₂
• Purity: Min. 95%
• InChI: InChI=1S/C6H3BrF2/c7-5-2-1-4(8)3-6(5)9/h1-3H
• InChI key: InChIKey=MGHBDQZXPCTTIH-UHFFFAOYSA-N
• SMILES: Fc1ccc(Br)c(F)c1