Dapsone

CAS: 80-08-0

Ref. 3D-FD20798

Product Information

• Name: Dapsone
• Synonyms: DADPSDDSAvlosulfonCroysulfoneDiphenasoneDisuloneDumitoneEporalSulphadione,4,4'-sulfonylbisbenzeneamine, 1,1'-Sulfonylbis[4-aminobenzene], 1358F, 4,4'-Dapsone, 4,4'-Dds, 4,4'-Diamino Diphenyl Sulfone, 4,4'-Diamino Diphenyl Sulphone, 4,4'-Diaminodiphenylsulfon, 4,4'-Diaminodiphenylsulfone, 4,4'-Sulfonylbisaniline, 4,4'-Sulfonylbisbenzamine, 4,4'-Sulfonyldiphenylamine, 4,4-Diaminodiphenyl sulfone, 4,4-Diaminodiphenyl sulphone, 4,4-Sulfonyldianiline, 4,4-Sulphonyldianiline, 4,4′-Diaminobiphenyl sulfone, 4,4′-Sulfonylbis[benzenamine], 4-((4-Aminophenyl)Sulfonyl)Phenylamine, 4-(4-Aminophenyl)sulfonylaniline, 4-(4-Aminophenylsulfonyl)benzenamine, 4-Aminophenyl sulphone, 44Dds, Aczone, Aniline, 4,4'-sulfonyldi-, Aradur 9664-1, Aradur 9664-1NL, Aradur 976, Aradur 976-1, Aradur 9761-1, Araldite HT 976, Atrisone, Avlosulfon, Avlosulfone, Avlosulphone, Benzenamine, 4,4'-sulfonylbis-, Bis(4-aminophenyl) sulfone, Bis(P-Aminophenyl)Sulfone, Croysulfone, Croysulphone, D 0089, DDS, DDS (pharmaceutical), DSS, Dadfs, Dadps, Dapson, Di(4-Aminophenyl) Sulphone, Di(4-aminophenyl)sulfone, Di(p-aminophenyl) sulfone, Diaminodiphenylsulfone, Diaphenylsulfon, Diaphenylsulfone, Diphenasone, Diphenyl Sulfone, 4,4'-Diamino-, Diphone, Disulone, Dumitone, Eporal, F 1358, Hardener HT 976, Hb-Mc-Ge 40, Hb-Mc-Ge 45, Hew 62, Ht 9664, Ht 976, Ht 976-1, Hy 976, Lapox K 10, Metabolite C, Novophone, Nsc 6091, P,P'-Sulfonyldianiline, P-Aminophenyl Sulfone, Seikacure S, Servidapson, Sulfona, Sulfona-Mae, Sulphadione, Sumicure S, Timtec-Bb Sbb003168, Udolac, p,p'-Diaminodiphenyl sulfone

Description

Dapsone is a nonsteroidal anti-inflammatory drug that is used to treat various types of infectious diseases and skin disorders. It acts by blocking the synthesis of dihydrofolic acid, which leads to inhibition of bacterial growth. Dapsone inhibits the activity of monoethyl ether reductase (NADH) in human polymorphonuclear leukocytes, which slows the production of hydrogen peroxide and prevents oxidative damage to cellular components. It has been shown to be effective against both erythema multiforme and chronic dermatitis herpetiformis with minimal side effects. The use of dapsone may be helpful in diagnosis as it can inhibit polymerase chain reactions that are specific for squamous cells. There are also reports that dapsone may affect intestinal motility and cause bowel disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 248.3 g/mol
• Formula: C₁₂H₁₂N₂O₂S
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
• InChI key: InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1