2-Demethyl colchicine

CAS: 102491-80-5

Ref. 3D-FD20990

Product Information

• Name: 2-Demethyl colchicine
• Synonyms: N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamideO2-Demethylcolchicine(-)-2-Demethylcolc hicine, N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide, Nsc 18053, O2-Demethylcolchicine, Nsc 180533, N-[(7S)-2-hydroxy-1,3,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide

Description

2-Demethyl colchicine is a natural compound that belongs to the group of flavonoids. It has been shown to have anti-inflammatory properties and has been studied for its ability to inhibit the formation of leukotrienes, which are important mediators in allergic reactions. 2-Demethyl colchicine also reduces inflammation caused by excessive production of nitric oxide, which can lead to inflammatory diseases such as atherosclerosis. 2-Demethyl colchicine has a high affinity for potassium dichromate, with a formation rate of 1:1.

• Brand: Biosynth

Chemical properties

• Molecular weight: 385.41 g/mol
• Formula: C₂₁H₂₃NO₆
• Purity: Min. 94 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(27-3)20(25)21(28-4)19(12)13-6-8-17(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1
• InChI key: InChIKey=DPOVAJCRYIUTBD-HNNXBMFYSA-N
• SMILES: COc1cc2c(c(OC)c1O)-c1ccc(OC)c(=O)cc1[C@@H](NC(C)=O)CC2