Desonide

CAS: 638-94-8

Ref. 3D-FD21374

Product Information

• Name: Desonide
• Synonyms: (11b,16a)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione16a-Hydroxyprednisolone acetonideLocapred, (11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, 11β,16α,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide, 11β,21-Dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione, 16α,17α-(Isopropylidenedioxy)prednisolone, 16α-Hydroxyprednisolone 16,17-acetonide, 16α-Hydroxyprednisolone 16α,17α-acetonide, 16α-Hydroxyprednisolone acetonide, 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv., Apolar, Budesonide acetonide, D 2083, Desonid, Desonida, Desowen, Locapred, Prednacinolone, Prednacinolone acetonide, Prednisolone acetonide, Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, Prenacid, Sterax, Steroderm, Topifug, Tridesilon, Tridesonit

Description

Desonide is a synthetic, low-potency corticosteroid with antiinflammatory activity. It is chemically stable and has only minimal potential for skin irritation. The pharmacokinetics of desonide have been studied in humans and rats. Desonide is metabolized to betamethasone, its active form, which binds to glucocorticoid receptors in the nucleus of cells. This binding inhibits the transcription of genes that regulate inflammatory responses, leading to relief from symptoms such as redness, swelling, and itching. Desonide has shown efficacy in the treatment of alopecia areata (hair loss) with topical application.

• Brand: Biosynth

Chemical properties

• Molecular weight: 416.51 g/mol
• Formula: C₂₄H₃₂O₆
• Purity: Min. 95%
• Color/Form: White Powder