Diethyl squarate

CAS: 5231-87-8

Ref. 3D-FD29532

Product Information

• Name: Diethyl squarate
• Synonyms: 3,4-Diethoxy-3-cyclobutene-1,2-dioneSquaric acid diethyl ester, 1,2-Diethoxy-1-cyclobutene-3,4-dione, 1,2-Diethoxy-3,4-dioxocyclobut-1-ene, 1,2-Diethoxycyclobutenedione, 3,4-Diethoxycyclobut-3-Ene-1,2-Dione, 3,4-Diethoxycyclobutene-1,2-dione, 3-Cyclobutene-1,2-dione, 3,4-diethoxy-, Cyclobutenedione, diethoxy-, Diethoxycyclobut-3-ene-1,2-dione, Diethoxycyclobutenedione, Diethyl quadratate, Squaric acid diethyl ester
• CAS: 5231-87-8

Description

Diethyl squarate is a squaramide that has been used in the treatment of infectious diseases. It is also known to be an anti-inflammatory agent, which has been shown to inhibit the production of prostaglandin, and is therefore useful in the treatment of autoimmune diseases such as alopecia areata. Diethyl squarate also has a role in immune responses as it binds to human serum albumin and alters antibody response. The compound is thought to bind to the hydroxyl group on a protein molecule, forming a covalent linkage with the amide group on another protein molecule. This reaction mechanism may lead to its immunosuppressant properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 170.16 g/mol
• Formula: C₈H₁₀O₄
• Purity: Min. 97 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C8H10O4/c1-3-11-7-5(9)6(10)8(7)12-4-2/h3-4H2,1-2H3
• InChI key: InChIKey=DFSFLZCLKYZYRD-UHFFFAOYSA-N
• SMILES: CCOc1c(OCC)c(=O)c1=O