Edaravone

CAS: 89-25-8

Ref. 3D-FE22642

Product Information

• Name: Edaravone
• Synonyms: 2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-oneMethylphenylpyrazolone, 1,3,5-Pmp, 1-Fenil-3-Metil-5-Pirazolona, 1-Phenyl-3-Methyl-5-Prazalone, 1-Phenyl-3-Methyl-5-Pyrazole, 1-Phenyl-3-Methyl-5-Pyrazolone, 1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-one, 1-Phenyl-3-methyl-2-pyrazolin-5-one, 1-Phenyl-3-methyl-5-oxopyrazole, 1-Phenyl-3-methyl-5-pyrazolinone, 2,4-Dihydro-5-Methyl-2-Phenyl-3H-Pyrazol-3-On, 2,4-Dihydro-5-Methyl-2-Phenyl-3H-Pyrazol-3-One, 2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazole-3-one, 2-Pyrazolin-5-one, 3-methyl-1-phenyl-, 3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one, 3-Methyl-1-phenyl-1H-pyrazol-5-one, 3-Methyl-1-phenyl-2-pyrazoline-5-one, 3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one, 3-Methyl-1-phenyl-4,5-dihydropyrazol-5-one, 3-Methyl-1-phenyl-4,5-dihydropyrazole-5-one, 3-Methyl-1-phenyl-5-pyrazolon, 3-Methyl-1-phenyl-5-pyrazolone, 3-Methyl-1-phenylpyrazol-5(4H)-one, 3-Methyl-1-phenylpyrazol-5-one, 3-Methyl-1-phenylpyrazole-5-one, 3-Methyl-1-phenylpyrazolin-5-one, 3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-2-phenyl-, 4,5-Dihydro-3-methyl-5-oxo-1-phenylpyrazole, 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one, 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, 5-Methyl-2-phenyl-2,4-dihydropyrazol-3-one, 5-Methyl-2-phenyl-2H-pyrazol-3(4H)-one, 5-Methyl-2-phenylpyrazol-3-one, Developer Z, Edarabone, Edaravon, Edvaradone, Mci-186, Methylphenylpyrazolone, Nci-C 03952, Norantipyrine, Norphenazone, Nsc 12, Nsc 26139, Nsc 2629, PMP, Phenylmethyl pyrazolone, Pyrazolin(2)-5-One, 3-Methyl-1-Phenyl-, Radicava, Radicut, C.I. Developer 1, C.I. Developer 1

Description

Edaravone is a drug that belongs to the class of radical scavengers and has been shown to be effective in reducing neuronal death by blocking the mitochondrial permeability transition pore. It also protects against oxidative injury by inhibiting lipid peroxidation, protein nitration, and DNA damage. Edaravone has been shown to be effective in treating bowel disease and possibly other inflammatory diseases such as sepsis. Edaravone is injected intravenously and can be used as an injection solution with dextran sulfate due to its low solubility in water. Edaravone binds reversibly to the toll-like receptor 4 (TLR4) and inhibits TLR4-mediated signaling pathways, which may lead to a reduction of inflammation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 174.2 g/mol
• Formula: C₁₀H₁₀N₂O
• Purity: Min. 98%
• Color/Form: Powder
• InChI: InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3
• InChI key: InChIKey=QELUYTUMUWHWMC-UHFFFAOYSA-N
• SMILES: CC1=NN(c2ccccc2)C(=O)C1