CAS 89-25-8: Edaravone

Description: Edaravone, with the CAS number 89-25-8, is a synthetic compound primarily recognized for its neuroprotective properties. It is classified as a free radical scavenger, which means it can neutralize harmful free radicals in the body, thereby reducing oxidative stress. This characteristic makes it particularly relevant in the treatment of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and acute ischemic stroke. Edaravone is typically presented as a colorless to pale yellow liquid and is soluble in water, which facilitates its administration in clinical settings. The compound has a relatively low molecular weight and exhibits a moderate level of lipophilicity, allowing it to penetrate biological membranes effectively. Its mechanism of action involves the inhibition of lipid peroxidation and the protection of neuronal cells from oxidative damage. Edaravone has been studied extensively for its therapeutic potential, and while it is generally well-tolerated, it may have side effects that require monitoring during treatment.

Formula: C₁₀H₁₀N₂O

InChI: InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChI key: InChIKey=QELUYTUMUWHWMC-UHFFFAOYSA-N

SMILES: O=C1N(N=C(C)C1)C=2C=CC=CC2

Synonyms:

• 1,3,5-Pmp
• 1-Fenil-3-Metil-5-Pirazolona
• 1-Phenyl-3-Methyl-5-Prazalone
• 1-Phenyl-3-Methyl-5-Pyrazole
• 1-Phenyl-3-Methyl-5-Pyrazolone
• 1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-one
• 1-Phenyl-3-methyl-2-pyrazolin-5-one
• 1-Phenyl-3-methyl-5-oxopyrazole
• 1-Phenyl-3-methyl-5-pyrazolinone
• 2,4-Dihydro-5-Methyl-2-Phenyl-3H-Pyrazol-3-On
• 2,4-Dihydro-5-Methyl-2-Phenyl-3H-Pyrazol-3-One
• 2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazole-3-one
• 2-Pyrazolin-5-one, 3-methyl-1-phenyl-
• 3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one
• 3-Methyl-1-phenyl-1H-pyrazol-5-one
• 3-Methyl-1-phenyl-2-pyrazoline-5-one
• 3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
• 3-Methyl-1-phenyl-4,5-dihydropyrazol-5-one
• 3-Methyl-1-phenyl-4,5-dihydropyrazole-5-one
• 3-Methyl-1-phenyl-5-pyrazolon
• 3-Methyl-1-phenyl-5-pyrazolone
• 3-Methyl-1-phenylpyrazol-5(4H)-one
• 3-Methyl-1-phenylpyrazol-5-one
• 3-Methyl-1-phenylpyrazole-5-one
• 3-Methyl-1-phenylpyrazolin-5-one
• 3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-2-phenyl-
• 4,5-Dihydro-3-methyl-5-oxo-1-phenylpyrazole
• 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
• 5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
• 5-Methyl-2-phenyl-2,4-dihydropyrazol-3-one
• 5-Methyl-2-phenyl-2H-pyrazol-3(4H)-one
• 5-Methyl-2-phenylpyrazol-3-one
• Developer Z
• Edarabone
• Edaravon
• Edaravone
• Edvaradone
• Mci-186
• Methylphenylpyrazolone
• Nci-C 03952
• Norantipyrine
• Norphenazone
• Nsc 12
• Nsc 26139
• Nsc 2629
• PMP
• Phenylmethyl pyrazolone
• Pyrazolin(2)-5-One, 3-Methyl-1-Phenyl-
• Radicava
• Radicut
• C.I. Developer 1
• C.I. Developer 1

3-Methyl-1-phenyl-5-pyrazolone

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 174.20

3-Methyl-1-phenyl-2-pyrazolin-5-one, 98+%

CAS: 89-25-8

3-Methyl-1-phenyl-2-pyrazolin-5-one used as reagent for detection of reducing carbohydrates by ESI/MALDI -MS. This Thermo Scientific …

• Formula: C₁₀H₁₀N₂O
• Purity: 98+%
• Color and Shape: Pale cream to cream to yellow to pale brown, Powder
• Molecular weight: 174.20

Phenazone impurity A CRS

CAS: 89-25-8

Antipyrine Related Compound A (3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one)

CAS: 89-25-8

Aromatic or modified aromatic compounds containg an unfused pyrazolering (whether or not hydrogenated) in the …

• Formula: C₁₀H₁₀N₂O
• Color and Shape: White Pale Yellow Powder
• Molecular weight: 174.07931

Edaravone

CAS: 89-25-8

Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients …

• Formula: C₁₀H₁₀N₂O
• Purity: 100% - 99.74%
• Color and Shape: Pale Yellow Solid Solid Particulate/Powder
• Molecular weight: 174.2

Edaravone

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 174.1992

1-Phenyl-3-methyl-5-pyrazolone

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Purity: 99.02% (Typical Value in Batch COA)
• Color and Shape: yellow crystalline powder
• Molecular weight: 174.20g/mol

1-Phenyl-3-methyl-5-pyrazolone

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Purity: ≥ 98.0%
• Color and Shape: White to yellow to brown powder or crystals
• Molecular weight: 174.20

Edaravone

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Color and Shape: White To Off-White Solid
• Molecular weight: 174.20

Edaravone

CAS: 89-25-8

• Purity: ≥98%
• Molecular weight: 174.2g/mol

5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (Edaravone)

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Color and Shape: Neat
• Molecular weight: 174.20

3-Methyl-1-phenyl-2-pyrazolin-5-one, 99%

CAS: 89-25-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₀H₁₀N₂O
• Purity: 99%
• Color and Shape: Crystalline powder, Yellow to beige
• Molecular weight: 174.20

Edaravone

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Color and Shape: Neat
• Molecular weight: 174.20

3-Methyl-1-phenyl-2-pyrazoline-5-one

CAS: 89-25-8

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 174.203

3-​Methyl-​1-​phenyl-​2-​pyrazolin-​5-​one(Edaravone)

CAS: 89-25-8

Impurity Phenazone EP Impurity A Applications Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone …

• Formula: C₁₀H₁₀N₂O
• Color and Shape: Neat
• Molecular weight: 174.20

Antipyrine USP Related Compound A

CAS: 89-25-8

• Formula: C₁₀H₁₀N₂O
• Molecular weight: 174.2

Edaravone

CAS: 89-25-8

Please enquire for more information about Edaravone including the price, delivery time and more detailed …

• Formula: C₁₀H₁₀N₂O
• Purity: Min. 98%
• Color and Shape: Powder
• Molecular weight: 174.2 g/mol

Edaravone

CAS: 89-25-8

Aromatic or modified aromatic compounds containg an unfused pyrazolering (whether or not hydrogenated) in the …

• Formula: C₁₀H₁₀N₂O
• Molecular weight: 174.07931