4-Fluoro-3-nitrobenzyl alcohol

CAS: 20274-69-5

Ref. 3D-FF10251

Product Information

• Name: 4-Fluoro-3-nitrobenzyl alcohol
• Brand: Biosynth
• Description: 4-Fluoro-3-nitrobenzyl alcohol (4FNA) is a potent, orally bioavailable, and selective inhibitor of the tyrosine kinase AXL. 4FNA binds to the ATP binding site on AXL and blocks phosphorylation of its tyrosine kinase domain. This binding leads to a conformational change in the AXL protein that prevents it from interacting with downstream signaling molecules, inhibiting T cell activation.

Chemical properties

• Molecular weight: 171.13 g/mol
• Formula: C₇H₆FNO₃
• Purity: Min. 95%