4-Fluoro-3-nitrobenzyl alcohol
CAS: 20274-69-5
Ref. 3D-FF10251
2g | 136.00 € | ||
5g | 180.00 € | ||
10g | 260.00 € | ||
25g | 452.00 € | ||
50g | 723.00 € |
Product Information
- (4-Fluor-3-nitrophenyl)methanol
- Benzenemethanol, 4-fluoro-3-nitro-
4-Fluoro-3-nitrobenzyl alcohol (4FNA) is a potent, orally bioavailable, and selective inhibitor of the tyrosine kinase AXL. 4FNA binds to the ATP binding site on AXL and blocks phosphorylation of its tyrosine kinase domain. This binding leads to a conformational change in the AXL protein that prevents it from interacting with downstream signaling molecules, inhibiting T cell activation.
Chemical properties
Technical inquiry about: 3D-FF10251 4-Fluoro-3-nitrobenzyl alcohol
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