Fluindione

CAS: 957-56-2

Ref. 3D-FF23325

Product Information

• Name: Fluindione
• Synonyms: 2-(4-Fluorophenyl)-1H-indene-1,3(2H)-dione2-(p-Fluorophenyl)-1,3-indandioneLM 123, 1,3-Indandione, 2-(p-fluorophenyl)-, 1H-Indene-1,3(2H)-dione, 2-(4-fluorophenyl)-, 2-(4-fluorophenyl)-1H-indene-1,3(2H)-dione, 2-(p-Fluorophenyl)-1,3-indandione, Brn 2052411, Fluindiona, Fluindiona [INN-Spanish], Fluindione [INN], Fluindionum, Fluindionum [INN-Latin], Lm 123, Previscan, Unii-Eq35Yms20Q

Description

Fluindione is an oral hypolipidemic drug that belongs to the coumarin derivatives. The drug has been shown to reduce serum cholesterol and triglyceride levels, as well as body mass index (BMI). Fluindione is a prodrug that is converted in vivo to its active form, 7-hydroxycoumarin. The metabolism of fluindione may be affected by other drugs such as ketoconazole, erythromycin, and cimetidine. Fluindione has been shown to have a beneficial effect on patients who suffer from bowel disease or cardiac diseases such as atrial fibrillation. Patients who are elderly or hypersensitive are advised to avoid this medication due to its side effects, which include symptoms such as rash, fever, hypotension, tachycardia and high values of liver enzymes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 240.23 g/mol
• Formula: C₁₅H₉FO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C15H9FO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H
• InChI key: InChIKey=NASXCEITKQITLD-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2C(=O)C1c1ccc(F)cc1