Furazolidone

CAS: 67-45-8

Ref. 3D-FF23622

Product Information

• Name: Furazolidone
• Synonyms: 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinoneDiafuron, 2-Furanmethanimine,5-Nitro-N-(2-Oxo-3-Oxazolidinyl)-, 2-Oxazolidinone, 3-[(5-nitrofurfurylidene)amino]-, 2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-, 2-Oxazolidone, 3-[[(5-nitro-2-furanyl)methylene]amino]-, 3-(5'-Nitrofurfurylideneamino)-2-oxazolidinone, 3-(5-Nitrofurfurylideneamino)-2-Oxazolidone, 3-(5-aci-Nitro-2(5H)-furylidenemethylimino)-2-oxooxazolidinium hydroxide, inner salt, 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone, 3-[2-(5-Nitrofuran-2-Yl)Ethenyl]-1,3-Oxazolidin-2-One, 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone, 3-{[(1E)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one, 3-{[(5-Nitrofuran-2-Yl)Methylidene]Amino}-1,3-Oxazolidin-2-One, Dependal-M, Diafuron, Foroxone, Furaxon, Furaxone, Furazol, Furazolidinone, Furazolidon, Furazolidona, Furazolidonum, Furazon, Furidon, Furovag, Furox, Furoxal, Furoxane, Furoxon, Furoxone, Furoxone Swine Mix, Furozolidine, Giardil, Giarlam, Medaron, N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone, Neftin, Nf 180, Nicolen, Nifulidone, Nifurazolidone, Nitrofurazolidone, Nitrofuroxon, Nsc 6469, Optazol, Ortazol, Puradin, Roptazol, Tikofuran, Topazone, Trifurox

Description

Furazolidone is an antimicrobial agent that belongs to the group of synthetic nitrofurans. Furazolidone inhibits bacterial growth by binding to nuclear DNA, which prevents transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Furazolidone also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 225.16 g/mol
• Formula: C₈H₇N₃O₅
• Purity: Min. 95%
• Color/Form: Yellow Powder