CAS 67-45-8
:Furazolidone
Description:
Furazolidone is a synthetic nitrofuran derivative with the chemical formula C8H8N4O5. It is primarily known for its antimicrobial properties and is used in the treatment of various bacterial and protozoal infections. The compound exhibits a yellow to orange crystalline appearance and is soluble in water and alcohol, which facilitates its use in pharmaceutical formulations. Furazolidone functions by inhibiting bacterial enzyme systems, particularly those involved in energy metabolism, and it is effective against a range of pathogens, including some strains of Escherichia coli and Giardia lamblia. However, its use has declined due to concerns over potential side effects, including gastrointestinal disturbances and the risk of mutagenicity. Additionally, it is important to note that furazolidone is not approved for use in food-producing animals in several countries due to these safety concerns. As with any medication, it is essential to use furazolidone under the guidance of a healthcare professional to ensure appropriate application and monitoring for adverse effects.
Formula:C8H7N3O5
InChI:InChI=1/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI key:InChIKey=PLHJDBGFXBMTGZ-UHFFFAOYSA-N
SMILES:C(=NN1C(=O)OCC1)C=2OC(N(=O)=O)=CC2
Synonyms:- 2-Furanmethanimine,5-Nitro-N-(2-Oxo-3-Oxazolidinyl)-
- 2-Oxazolidinone, 3-[(5-nitrofurfurylidene)amino]-
- 2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
- 2-Oxazolidone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
- 3-(5'-Nitrofurfurylideneamino)-2-oxazolidinone
- 3-(5-Nitrofurfurylideneamino)-2-Oxazolidone
- 3-(5-aci-Nitro-2(5H)-furylidenemethylimino)-2-oxooxazolidinium hydroxide, inner salt
- 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone
- 3-[2-(5-Nitrofuran-2-Yl)Ethenyl]-1,3-Oxazolidin-2-One
- 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone
- 3-{[(1E)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
- 3-{[(5-Nitrofuran-2-Yl)Methylidene]Amino}-1,3-Oxazolidin-2-One
- Dependal-M
- Diafuron
- Foroxone
- Furaxon
- Furaxone
- Furazol
- Furazolidinone
- Furazolidon
- Furazolidona
- Furazolidonum
- Furazon
- Furidon
- Furovag
- Furox
- Furoxal
- Furoxane
- Furoxon
- Furoxone
- Furoxone Swine Mix
- Furozolidine
- Giardil
- Giarlam
- Medaron
- N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone
- Neftin
- Nf 180
- Nicolen
- Nifulidone
- Nifurazolidone
- Nitrofurazolidone
- Nitrofuroxon
- Nsc 6469
- Optazol
- Ortazol
- Puradin
- Roptazol
- Tikofuran
- Topazone
- Trifurox
- furazolidone(notsubjecttofifra:8709-e
- 3-[[(5-Nitrofuran-2-yl)methylene]amino]oxazolidine-2-one
- furazolidone(notsubjectto
- 3-[[(5-Nitrofuran-2-yl)methylene]amino]oxazolidin-2-one
- FURAZOLIDONE,USP
- NF 180 custom mix ten
- Furazolidone solution, 100ug/ml
- 3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinon
- Furazolldone
- Nitrofurazolidonum
- 3-(5'-Nitrofurfuralamino)-2-oxazolidone
- 2-Oxazolidinone, 3-((5-nitrofurfurylidine)amino)-
- Sclaventerol
- component of Topazone
- FURAZOLIDONE BP 98
- USAF ea-1
- Nifuran
- 3-(((5-nitro-2-furanyl)methylene)amino)-2-oxazolidinon
- 3-((5-nitrofurfurylidene)amino)-2-oxazolidinon
- FURAZOLIDONE VETRANAL, 250 MG
- usafea-1
- Furazolidone,98%
- FURAZIDIN(FURAGIN)
- 3-(5-Nitrofurfurylideneamino)oxazolidin-2-one
- 3-(5-Nitrofurfurylideneamino)-4,5-dihydrooxazol-2(3H)-one
- N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one
- Furall
- 1-(furan-2-yl)pyrrolidin-2-one
- N-(5-NITRO-2-FURFURYLIDENE)-3-AMINO-2-OXAZOLIDIN-2-ONE
- Furazolidine
- 3-([(E)-(5-Nitro-2-furyl)methylidene]amino)-1,3-oxazolidin-2-one
- Corizium
- furazolidone(notsubjecttofifra:8709-epm24)
- 3-(5-NITROFURYLIDENEAMINO)-2-OXAZOLIDINONE
- Furazolidone Vetec(TM) reagent grade
- Bifuron
- Furazolidone (200 mg)
- Tricofuron
- nf180custommixten
- 3-(5-Nitrofurfurylideneamino)-2-oxazolidione
- FURAZOLIDONE BP/USP
- component of Tricofuron
- Coryzium
- LABOTEST-BB LT00244769
- Furazolidone solution,100ppm
- 3-((5-Nitrofurylidene)amino)-2-oxazolidone
- Furazolidone,3-(5-Nitrofurfurylideneamino)-2-oxazolidinone
- Fiurox aerosol powder
- Trichofuron
- Furanzolidone
- 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine
- Enterotoxon
- 3-(5-NITROFURFURYLIDENEAMINO)OXAZOLIDIN-2-ONE(FURAZOLIDONE)
- 3-((5-Nitrofurfurylidene)amino)-2-oxazolidone
- 3-(5’-nitrofurfuralamino)-2-oxazolidone
- FURAZOLIDONE
- Viofuragyn
- furoxoneswinemix
- See more synonyms
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Furazolidone
CAS:Formula:C8H7N3O5Purity:>98.0%(HPLC)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:225.16Furazolidone, 98%
CAS:Monoamine oxidase inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brFormula:C8H7N3O5Purity:98%Color and Shape:Powder, YellowMolecular weight:225.16Furazolidone
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compoundsFormula:C8H7N3O5Color and Shape:Yellow PowderMolecular weight:225.03857Furazolidone
CAS:FurazolidoneFormula:C8H7N3O5Purity:99.5%Color and Shape:SolidMolecular weight:225.16Furazolidone
CAS:Formula:C8H7N3O5Purity:≥ 98.0% (dried basis)Color and Shape:Yellow crystalline powderMolecular weight:225.16Furazolidone
CAS:Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.Formula:C8H7N3O5Purity:99.96% - 99.98%Color and Shape:SolidMolecular weight:225.1583PharmaVetResiMix 7 Nitroimidazoles-v13 10 µg/mL in Methanol
CAS:Controlled Product- 14885-29-1
- 16773-42-5
- 19387-91-8
- 35175-14-5
- 42116-76-7
- 443-48-1
- 4812-40-2
- 551-92-8
- 59-87-0
- 67-45-8
- 70028-95-4
- 7681-76-7
- 936-05-0
Color and Shape:Mixture2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
CAS:Formula:C8H7N3O5Purity:97%Color and Shape:SolidMolecular weight:225.1583Furazolidone (Standard)
CAS:Furazolidone (Standard) is the standard substance of Furazolidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,Formula:C8H7N3O5Molecular weight:225.1583Furazolidone
CAS:Applications Antimicrobial.Environmental contaminants; Food contaminants; Heat processing contaminants
References Yurchenco, J.A., et al.: Antimicrob. Chemother., 3, 1035 (1953), Sharma, C., et al.: J. Clin. Microbiol., 36, 756 (1998),Formula:C8H7N3O5Color and Shape:NeatMolecular weight:225.163-(((5-Nitrofuran-2-yl)methylene)amino)oxazolidin-2-one
CAS:3-(((5-Nitrofuran-2-yl)methylene)amino)oxazolidin-2-oneFormula:C8H7N3O5Purity:99%Molecular weight:225.163-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
CAS:Formula:C8H7N3O5Purity:97%Color and Shape:LiquidMolecular weight:225.16Furazolidone
CAS:Furazolidone is an antimicrobial agent that belongs to the group of synthetic nitrofurans. Furazolidone inhibits bacterial growth by binding to nuclear DNA, which prevents transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Furazolidone also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formula:C8H7N3O5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:225.16 g/mol
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