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CAS 67-45-8

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Furazolidone

Description:
Furazolidone is a synthetic nitrofuran derivative with the chemical formula C8H8N4O5. It is primarily known for its antimicrobial properties and is used in the treatment of various bacterial and protozoal infections. The compound exhibits a yellow to orange crystalline appearance and is soluble in water and alcohol, which facilitates its use in pharmaceutical formulations. Furazolidone functions by inhibiting bacterial enzyme systems, particularly those involved in energy metabolism, and it is effective against a range of pathogens, including some strains of Escherichia coli and Giardia lamblia. However, its use has declined due to concerns over potential side effects, including gastrointestinal disturbances and the risk of mutagenicity. Additionally, it is important to note that furazolidone is not approved for use in food-producing animals in several countries due to these safety concerns. As with any medication, it is essential to use furazolidone under the guidance of a healthcare professional to ensure appropriate application and monitoring for adverse effects.
Formula:C8H7N3O5
InChI:InChI=1/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI key:InChIKey=PLHJDBGFXBMTGZ-UHFFFAOYSA-N
SMILES:C(=NN1C(=O)OCC1)C=2OC(N(=O)=O)=CC2
Synonyms:
  • 2-Furanmethanimine,5-Nitro-N-(2-Oxo-3-Oxazolidinyl)-
  • 2-Oxazolidinone, 3-[(5-nitrofurfurylidene)amino]-
  • 2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
  • 2-Oxazolidone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
  • 3-(5'-Nitrofurfurylideneamino)-2-oxazolidinone
  • 3-(5-Nitrofurfurylideneamino)-2-Oxazolidone
  • 3-(5-aci-Nitro-2(5H)-furylidenemethylimino)-2-oxooxazolidinium hydroxide, inner salt
  • 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone
  • 3-[2-(5-Nitrofuran-2-Yl)Ethenyl]-1,3-Oxazolidin-2-One
  • 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone
  • See more synonyms
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