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CAS 67-45-8

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Furazolidone

Description:
Furazolidone is a synthetic nitrofuran derivative with the chemical formula C8H8N4O5. It is primarily known for its antimicrobial properties and is used in the treatment of various bacterial and protozoal infections. The compound exhibits a yellow to orange crystalline appearance and is soluble in water and alcohol, which facilitates its use in pharmaceutical formulations. Furazolidone functions by inhibiting bacterial enzyme systems, particularly those involved in energy metabolism, and it is effective against a range of pathogens, including some strains of Escherichia coli and Giardia lamblia. However, its use has declined due to concerns over potential side effects, including gastrointestinal disturbances and the risk of mutagenicity. Additionally, it is important to note that furazolidone is not approved for use in food-producing animals in several countries due to these safety concerns. As with any medication, it is essential to use furazolidone under the guidance of a healthcare professional to ensure appropriate application and monitoring for adverse effects.
Formula:C8H7N3O5
InChI:InChI=1/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+
InChI key:InChIKey=PLHJDBGFXBMTGZ-UHFFFAOYSA-N
SMILES:C(=NN1C(=O)OCC1)C=2OC(N(=O)=O)=CC2
Synonyms:
  • 2-Furanmethanimine,5-Nitro-N-(2-Oxo-3-Oxazolidinyl)-
  • 2-Oxazolidinone, 3-[(5-nitrofurfurylidene)amino]-
  • 2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
  • 2-Oxazolidone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
  • 3-(5'-Nitrofurfurylideneamino)-2-oxazolidinone
  • 3-(5-Nitrofurfurylideneamino)-2-Oxazolidone
  • 3-(5-aci-Nitro-2(5H)-furylidenemethylimino)-2-oxooxazolidinium hydroxide, inner salt
  • 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone
  • 3-[2-(5-Nitrofuran-2-Yl)Ethenyl]-1,3-Oxazolidin-2-One
  • 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone
  • See more synonyms
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Found 17 products.
  • Furazolidone

    CAS:
    Formula:C8H7N3O5
    Purity:>98.0%(HPLC)
    Color and Shape:Light yellow to Amber to Dark green powder to crystal
    Molecular weight:225.16

    Ref: 3B-F0821

    25g
    78.00€
  • Furazolidone, 98%

    CAS:
    Monoamine oxidase inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the br
    Formula:C8H7N3O5
    Purity:98%
    Color and Shape:Powder, Yellow
    Molecular weight:225.16

    Ref: 02-B20834

    25g
    79.00€
    100g
    200.00€
  • Furazolidone

    CAS:
    Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi
    Formula:C8H7N3O5
    Color and Shape:Yellow Powder
    Molecular weight:225.03857
  • Furazolidone

    CAS:
    Furazolidone
    Formula:C8H7N3O5
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:225.16

    Ref: 54-BUP18858

    500mg
    64.00€
    1g
    89.00€
    5g
    190.00€
    10g
    273.00€
  • 2-​Oxazolidinone, 3-​[[(5-​nitro-​2-​furanyl)​methylene]​amino]​-

    CAS:
    Formula:C8H7N3O5
    Purity:99%
    Color and Shape:Solid
    Molecular weight:225.1583

    Ref: IN-DA00ILIS

    100mg
    28.00€
    25g
    52.00€
    100g
    111.00€
    500g
    226.00€
    1kg
    602.00€
  • Furazolidone

    CAS:
    Formula:C8H7N3O5
    Purity:≥ 98.0% (dried basis)
    Color and Shape:Yellow crystalline powder
    Molecular weight:225.16

    Ref: 7W-GA1580

    10g
    55.00€
    25g
    78.00€
    100g
    214.00€
  • Furazolidone

    CAS:
    Formula:C8H7N3O5
    Color and Shape:Yellow Solid
    Molecular weight:225.16

    Ref: 4Z-F-069001

    5mg
    To inquire
    100mg
    To inquire
    10mg
    343.00€
    25mg
    436.00€
    50mg
    623.00€
  • Furazolidone

    CAS:
    Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.
    Formula:C8H7N3O5
    Purity:99.96%
    Color and Shape:Yellow Crystals From Dmf (N N-Dimethylformamide) Solid
    Molecular weight:225.16

    Ref: TM-T0751

    500mg
    46.00€
    1g
    58.00€
    5g
    124.00€
    10g
    178.00€
  • Furazolidone (Standard)

    CAS:
    Furazolidone (Standard) is the standard substance of Furazolidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,
    Formula:C8H7N3O5
    Molecular weight:225.16

    Ref: TM-TMSM-1246

    100mg
    50.00€
  • PharmaVetResiMix 7 Nitroimidazoles-v13 10 µg/mL in Methanol

    Controlled Product
    CAS:
    Color and Shape:Mixture

    Ref: 04-A30000037ME

    1ml
    864.00€
  • Furazolidone

    CAS:
    Formula:C8H7N3O5
    Color and Shape:Yellow
    Molecular weight:225.16

    Ref: 04-C13970200

    250mg
    72.00€
  • Furazolidone

    CAS:
    Formula:C8H7N3O5
    Molecular weight:225.16

    Ref: ST-EA-CP-F112000

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Furazolidone

    CAS:

    Applications Antimicrobial.Environmental contaminants; Food contaminants; Heat processing contaminants
    References Yurchenco, J.A., et al.: Antimicrob. Chemother., 3, 1035 (1953), Sharma, C., et al.: J. Clin. Microbiol., 36, 756 (1998),

    Formula:C8H7N3O5
    Color and Shape:Neat
    Molecular weight:225.16

    Ref: TR-F864100

    100mg
    94.00€
    1g
    97.00€
    10g
    101.00€
  • Furazolidone

    CAS:
    Furazolidone is an antimicrobial agent that belongs to the group of synthetic nitrofurans. Furazolidone inhibits bacterial growth by binding to nuclear DNA, which prevents transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Furazolidone also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
    Formula:C8H7N3O5
    Purity:Min. 95%
    Color and Shape:Yellow Powder
    Molecular weight:225.16 g/mol

    Ref: 3D-FF23622

    100g
    186.00€
    250g
    315.00€
    500g
    478.00€
  • Furazolidone

    CAS:
    3-(((5-Nitrofuran-2-yl)methylene)amino)oxazolidin-2-one
    Formula:C8H7N3O5
    Purity:99%
    Molecular weight:225.16

    Ref: IN-DG131691

    25g
    63.00€
    100g
    90.00€
    500g
    308.00€
    1kg
    478.00€
  • 3-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one

    CAS:
    Formula:C8H7N3O5
    Purity:97%
    Color and Shape:No data available.
    Molecular weight:225.16

    Ref: 10-F358121

    25g
    61.00€
    100g
    212.00€
    500g
    556.00€
    1kg
    874.00€
  • Furazolidone

    CAS:
    Furazolidone
    Color and Shape:Yellow

    Ref: 47-172

    1
    Discontinued
    Discontinued product