Fmoc-Thr-OH

CAS: 73731-37-0

Ref. 3D-FF37962

Product Information

• Name: Fmoc-Thr-OH
• Synonyms: Fmoc-L-Threonine, Fmoc-Thr-OH monohydrate, Fmoc-L-Threonine-OH, Fmoc-L-Thr-OH, N-[(9H-Fluoren-9ylmethoxy)carbonyl]-L-threonine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]threonine, (2S,3S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-hydroxybutanoate, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-allothreonine, Fmoc-Thr-OH.H2O, Fmoc-L-threonine, 2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Hydroxy-Butanoic Acid

Description

Fmoc-Thr-OH is a synthetic amino acid that has been used in the synthesis of peptides and glycopeptides. It is also a good building block for the construction of sialic acid derivatives. The Fmoc group can be removed by treating the compound with trifluoroacetic acid (TFA), which yields an unprotected l-threonine residue. This is then reacted with a benzyl ester to form an amide bond, forming an Fmoc-protected lactam. The chloride group on the benzyl ester can then be displaced by a reactive electrophile, such as trifluoroacetic acid (TFA) or N-hydroxysuccinimide, to form the desired product.
The analytical hplc method for quantifying Fmoc-Thr-OH uses choline as an internal standard and detects peaks at Rt = 1.80 min. The molecular weight of F

• Brand: Biosynth

Chemical properties

• Molecular weight: 341.36 g/mol
• Formula: C₁₉H₁₉NO₅
• Purity: Min. 95%
• Color/Form: Powder