(+)-Fangchinoline

CAS: 436-77-1

Ref. 3D-FF65604

Product Information

• Name: (+)-Fangchinoline
• Synonyms: 6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol, (+)-Hanfangichin B, (+)-Limacine, (1beta)-6,6',12-Trimethoxy-2,2'-dimethylberbaman-7-ol, (4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,26-trimethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, 3,4,4a,5,16a,17,18,19-octahydro-12,21,26-trimethoxy-4,17-dimethyl-, (4aS,16aS)-, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, 3,4,4a,5,16a,17,18,19-octahydro-12,21,26-trimethoxy-4,17-dimethyl-, [4aS-(4aR*,16aR*)]-, 6,6',12-Trimethoxy-2,2'-Dimethylberbaman-7-Ol, 7-O-Demethyltetrandrine, Berbaman-7-ol, 6,6′,12-trimethoxy-2,2′-dimethyl-, (1β)-, Hanfangchin B, NSC 77036

Description

(+) Fangchinoline is a natural compound that inhibits the growth of cancer cells. It has been shown to have inhibitory properties against infectious diseases, including HIV, and squamous carcinoma. (+) Fangchinoline has also been shown to induce apoptosis in human osteosarcoma cells and mda-mb-231 breast cancer cells. This compound induces the process of autophagy in these cells, which leads to cell death by inhibiting protein synthesis and DNA replication. (+) Fangchinoline is also used for the treatment of Parkinson's disease and cardiac arrhythmias. The mechanism of action for these diseases are not yet known.

• Brand: Biosynth

Chemical properties

• Molecular weight: 608.72 g/mol
• Formula: C₃₇H₄₀N₂O₆
• Purity: Min. 95%