5-Fluoro-2-methylphenol
CAS: 452-85-7
Ref. 3D-FF70447
| 10g | 136.00 € | ||
| 1kg | 1,218.00 € | ||
| 50g | 168.00 € | ||
| 100g | 238.00 € | ||
| 250g | 432.00 € |
Product Information
- 2-Methyl-5-fluorophenol
- Phenol, 5-fluoro-2-methyl-
- Qr Cf F1
- Qr Cf F1 [Wln]
- o-Cresol, 5-fluoro-
The fluoroquinolone 5-Fluoro-2-methylphenol (5FM) is an inhibitor of angiotensin, an enzyme that is involved in the regulation of blood pressure and fluid balance. The structure of this compound was optimized to make it more potent and selective for angiotensin, while minimizing its adverse effects. This optimization was achieved using high throughput screening and x-ray crystallography. The fluorine atom in 5FM binds to aspartyl protease, which prevents the protease from breaking down proteins into smaller amino acid chains. This binding also inhibits the activity of other enzymes that are involved in protein synthesis, such as aspartyl proteases and salicylic acid esterases. 5FM has been shown to inhibit the growth of bacteria such as Staphylococcus aureus at concentrations that are not toxic to mammalian cells.
Chemical properties
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