Ganciclovir

CAS: 82410-32-0

Ref. 3D-FG16550

Product Information

• Name: Ganciclovir
• Synonyms: 2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]6H-purin-6-oneHydroxyacyclovirNatclovir, 2'-Ndg, 2'-Nor-2'-deoxyguanosine, 2-Amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6H-purin-6-one, 2-Amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one, 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one, 2-Amino-9-[[(1,3-dihydroxypropan-2-yl)oxy]methyl]-6,9-dihydro-3H-purin-6-one, 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-, 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)-methyl)guanine, 9-(1,3-Dihydroxy-2-propoxymethyl)guanine, Biolf 62, Bw 759, Bw 759U, Bw-B 759U, Denosine, Dhpg, Gancyclovir, Ganguard, Ganquard, Gengxiluowei, Hhemg, Hydroxyacyclovir, Nataclovir, Natclovir, Rs 21592, Vitrasert, Vitrasert Implant

Description

Ganciclovir is an antiviral drug that inhibits viral DNA synthesis, leading to cell death. It is used for the treatment of cytomegalovirus retinitis, herpes zoster (shingles), and condyloma acuminata. Ganciclovir is also used as a preventative measure against opportunistic infection with HIV or CMV in people with AIDS. It is given intravitreally, by injection into the eye, with human immunoglobulin G (IgG) to prevent CMV in persons who have been exposed to it. The combination therapy group includes ganciclovir and acyclovir. Drug interactions can occur when ganciclovir is administered intravenously with heparin-containing solutions or drugs containing polymyxin B sulfate or colistimethate sodium. Ganciclovir has shown antiviral resistance in SCC cells and may lead to neuronal death when used on rats in

• Brand: Biosynth

Chemical properties

• Molecular weight: 255.23 g/mol
• Formula: C₉H₁₃N₅O₄
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
• InChI key: InChIKey=IRSCQMHQWWYFCW-UHFFFAOYSA-N
• SMILES: Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1