L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

Ref. 3D-FG33471

Product Information

• Name: L-Glutamic acid di-tert-butyl ester hydrochloride
• Synonyms: L-Glu(OtBu)-OtBu·HCl, <span class="text-smallcaps">L</span>-Glutamic acid di-tert-butyl ester hydrochloride, <span class="text-smallcaps">L</span>-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1), <span class="text-smallcaps">L</span>-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride, Di-tert-butyl (S)-2-aminopentanedioate hydrochloride, Di-tert-butyl <span class="text-smallcaps">L</span>-glutamate hydrochloride, Di-tert-butyl glutamate hydrochloride, Glu(OtBu)-OtBu HCl, Glutamic acid di-tert-butyl ester hydrochloride, Glutamic acid, di-tert-butyl ester, hydrochloride, <span class="text-smallcaps">L</span>-, H-Glu(OtBu)-OtBu.HCl, H-Glu(OtBu)-OtBu・HCl, L-(g-O-Bu)-Glu-O-tert-Bu HCl, L-Glutamic Acid Di-Tert-Butyl Ester Hydrochloride, L-Glutamic Acid Di-tert-Butyl Ester HCl Salt, NSC 94681, di-tert-butyl L-glutamate hydrochloride (1:1), L-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride, Glutamic acid, di-tert-butyl ester, hydrochloride, L-, L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1)

Description

L-glutamic acid di-tert-butyl ester hydrochloride is a synthetic glutamic acid conjugate that can be used in the treatment of cancer. L-Glutamic acid di-tert-butyl ester hydrochloride is a substrate for many enzymes, such as glutamate transporters and glutaminase, which are found in tumor cells. It has been shown to decrease the uptake of docetaxel by tumor xenografts in mice. The expression of L-Glutamic acid di-tert-butyl ester hydrochloride has been observed in tissues during cancerous growth and it is expressed at higher levels than in normal tissues.

• Brand: Biosynth

Chemical properties

• Molecular weight: 295.8 g/mol
• Formula: C₁₃H₂₅NO₄·HCl
• Purity: Min. 95%
• Color/Form: White Powder