CAS 32677-01-3

L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1)

Description:

L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1), with CAS number 32677-01-3, is a derivative of the amino acid L-glutamic acid. This compound features a bis(1,1-dimethylethyl) ester modification, which enhances its lipophilicity and stability compared to the parent amino acid. As a hydrochloride salt, it is typically more soluble in water, facilitating its use in various biochemical applications. The presence of the ester groups may influence its reactivity and biological activity, potentially affecting its role in metabolic pathways or as a neurotransmitter. This compound is often studied for its potential applications in pharmaceuticals, particularly in the development of drugs that target glutamate receptors or related pathways. Its structural characteristics, including the bulky dimethylethyl groups, may also impact its interaction with biological systems, making it a subject of interest in medicinal chemistry and drug design. Overall, L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride is a chemically modified amino acid with unique properties suitable for various scientific investigations.

Formula: C₁₃H₂₅NO₄·ClH

InChI: InChI=1S/C13H25NO4.ClH/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6;/h9H,7-8,14H2,1-6H3;1H/t9-;/m0./s1

InChI key: InChIKey=LFEYMWCCUAOUKZ-FVGYRXGTSA-N

SMILES: C([C@H](CCC(OC(C)(C)C)=O)N)(OC(C)(C)C)=O.Cl

Synonyms:

• <span class="text-smallcaps">L</span>-Glutamic acid di-tert-butyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride
• Di-tert-butyl (S)-2-aminopentanedioate hydrochloride
• Di-tert-butyl <span class="text-smallcaps">L</span>-glutamate hydrochloride
• Di-tert-butyl glutamate hydrochloride
• Glu(OtBu)-OtBu HCl
• Glutamic acid di-tert-butyl ester hydrochloride
• Glutamic acid, di-tert-butyl ester, hydrochloride, <span class="text-smallcaps">L</span>-
• H-Glu(OtBu)-OtBu.HCl
• H-Glu(OtBu)-OtBu・HCl
• L-(g-O-Bu)-Glu-O-tert-Bu HCl
• L-Glutamic Acid Di-Tert-Butyl Ester Hydrochloride
• L-Glutamic Acid Di-tert-Butyl Ester HCl Salt
• NSC 94681
• di-tert-butyl L-glutamate hydrochloride (1:1)
• L-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride
• Glutamic acid, di-tert-butyl ester, hydrochloride, L-

H-Glu(OtBu)-OtBu·HCl

CAS: 32677-01-3

H-Glu(OtBu)-OtBu.HCl

Formula: C₁₃H₂₆ClNO₄

Purity: 98%

Molecular weight: 295.8

Ref: IN-DG14997

H-Glu(OtBu)-OtBu·HCl

CAS: 32677-01-3

Formula: C₁₃H₂₅NO₄·HCl

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 295.80

Ref: 3B-D6026

L-Glutamic acid di-tert-butyl ester hydrochloride, 98%

CAS: 32677-01-3

L-Glutamic acid di-tert-butyl ester may be useful in the synthesis of substance P antagonistic peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa A

Formula: C₁₃H₂₆ClNO₄

Purity: 98%

Color and Shape: White to pale cream or pale yellow, Powder or crystals or crystalline powder

Molecular weight: 295.80

Ref: 02-H63708

L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

Formula: C₁₃H₂₆ClNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 295.8028

Ref: IN-DA0037EF

Di-tert-butyl L-glutamate hydrochloride

CAS: 32677-01-3

Di-tert-butyl L-glutamate hydrochloride

Formula: C₁₃H₂₅NO₄·ClH

Purity: 98%

Color and Shape: White Solid

Molecular weight: 295.80283

Ref: 54-OR52525

L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

Formula: C₁₃H₂₅NO₄·HCl

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 295.80

Ref: 7W-GM3288

L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

L-glutamic acid di-tert-butyl ester hydrochloride is a synthetic glutamic acid conjugate that can be used in the treatment of cancer. L-Glutamic acid di-tert-butyl ester hydrochloride is a substrate for many enzymes, such as glutamate transporters and glutaminase, which are found in tumor cells. It has been shown to decrease the uptake of docetaxel by tumor xenografts in mice. The expression of L-Glutamic acid di-tert-butyl ester hydrochloride has been observed in tissues during cancerous growth and it is expressed at higher levels than in normal tissues.

Formula: C₁₃H₂₅NO₄·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 295.8 g/mol

Ref: 3D-FG33471

H-Glu(OtBu)-OtBu.HCl

CAS: 32677-01-3

M02970 - H-Glu(OtBu)-OtBu.HCl

Formula: C₁₃H₂₆ClNO₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 295.8

Ref: 10-M02970

Di-tert-butyl Glutamate Hydrochloride

Controlled Product

CAS: 32677-01-3

Applications Di-tert-butyl Glutamate Hydrochloride is a reagent in the synthesis of Fructose-glutamic Acid (F795660); an amadori compound (derivatives of aminodeoxysugars) that is formed in food (such as dehydrated fruits such as tomatoes and carrots) as a result of the Maillard reactions.
References Baltes, W.: Food Chem., 9, 59 (1982); Sanz, M., et al.: J. Agr. Food Chem., 49, 5228 (2001); Wellner, A., et al.: J. Agr. Food Chem., 59, 7992 (2011)

Formula: C₁₃H₂₆ClNO₄

Color and Shape: Neat

Molecular weight: 295.8

Ref: TR-D493735

H-Glu(OtBu)-OtBu · HCl

CAS: 32677-01-3

Bachem ID: 4000156.

Formula: C₁₃H₂₅NO₄·HCl

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 295.81

Ref: 01-4000156