Product Information
Name:5-Hydroxy-5-methylhydantoin
Synonyms:
- 5-Hydroxy-5-methyl-2,4-imidazolidinedione
Brand:Biosynth
Description:5-Hydroxy-5-methylhydantoin (5HMH) is a glycosylase that is used to repair damaged DNA. It reacts with the hydroxyl group of 5-methylcytosine and removes it, yielding thymine. The reaction proceeds through a nucleophilic attack on the carbon atom adjacent to the C5 methyl group. This reaction is dependent on neutral pH, uv absorption, and has been shown in vitro to be inhibited by the presence of oxidizing agents. 5HMH has been shown to remove UVB-induced damage from DNA in mammalian cells, which may lead to cancer.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:130.1 g/mol
Formula:C4H6N2O3
Purity:Min. 95%
InChI:InChI=1S/C4H6N2O3/c1-4(9)2(7)5-3(8)6-4/h9H,1H3,(H2,5,6,7,8)
InChI key:InChIKey=CNQHZBFQVYOFGD-UHFFFAOYSA-N
SMILES:CC1(O)NC(=O)NC1=O
Technical inquiry about: 5-Hydroxy-5-methylhydantoin
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