trans-4-Hydroxy-L-proline methyl ester hydrochloride

CAS: 40216-83-9

Ref. 3D-FH24381

Product Information

• Name: trans-4-Hydroxy-L-proline methyl ester hydrochloride
• Synonyms: L-Hydroxyproline methyl ester hydrochlorideMethyl (2S,4R)-4-hydroxy-2-pyrrolidinecarboxylate hydrochlorideMethyl L-hydroxyprolinat e hydrochloride, (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester hydrochloride, (2S,4R)-Methyl 4-Hydroxypyrrolidine-2-Carboxylate Hydrochloride, (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride, 4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride, 4-Hydroxy-L-Proline Methyl Ester Hcl, 4-Hydroxyproline ester hydrochloride, 4-Hydroxyproline methyl ester hydrochloride, 4-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride, <span class="text-smallcaps">L</span>-Hydroxyproline methyl ester hydrochloride, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)-, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride, (4R)-, <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride, trans-, H-D-trans-Hyp-OMe.HCl, H-Hyp-Ome・Hcl, H-L-Hyp-Ome Hcl, Hcl.Trans-D-Hyp-Ome, Hydroxyproline methyl ester hydrochloride, Hydroxyproline-Ome Hcl, L-4-Hydroxyproline Methyl Ester Hydrochloride, L-4-Hydroxyproline Methyl Ester Hydrochloride Salt, L-4-Trans-Hydroxyproline Methyl Ester Hydrochloride, L-4-Trans-Hydroxyproline Methyl Ester Hydrochloride Salt, L-Trans-4-Hydroxyproline Methyl Ester Hydrochloride Salt, Methyl (2S,4R)-4-Hydroxypyrrolidine-2-Carboxylate Hydrochloride, Methyl (2S,4R)-4-hydroxy-2-pyrrolidinecarboxylate hydrochloride, Methyl <span class="text-smallcaps">L</span>-hydroxyprolinate hydrochloride, Methyl trans-4-hydroxy-<span class="text-smallcaps">L</span>-prolinate hydrochloride, Proline, 4-hydroxy-, methyl ester, hydrochloride, Trans-4-Hydroxy-L-Proline Methyl Ester Hydrochloride, trans-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride, trans-4-Hydroxyproline methyl ester hydrochloride

Description

Trans-4-hydroxy-L-proline methyl ester hydrochloride is a matrix metalloproteinase inhibitor. It inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen and other proteins in the extracellular matrix. The inhibition of these enzymes leads to a decrease in restenosis, which is the recurrence of artery narrowing after angioplasty or stent placement. Trans-4-hydroxy-L-proline methyl ester hydrochloride has been shown to be effective against chemokine receptors, including CCR5 receptor and chemokines such as TNFα. It also inhibits cytokine production by inhibiting signaling pathways that lead to inflammation and cell proliferation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 181.62 g/mol
• Formula: C₆H₁₁NO₃·HCl
• Color/Form: White/Off-White Solid