trans-4-Hydroxy-L-proline methyl ester hydrochloride

CAS: 40216-83-9

Ref. 3D-FH24381

Product Information

• Name: trans-4-Hydroxy-L-proline methyl ester hydrochloride
• Synonyms: L-Hydroxyproline methyl ester hydrochlorideMethyl (2S,4R)-4-hydroxy-2-pyrrolidinecarboxylate hydrochlorideMethyl L-hydroxyprolinat e hydrochloride
• Brand: Biosynth
• Description: Trans-4-hydroxy-L-proline methyl ester hydrochloride is a matrix metalloproteinase inhibitor. It inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen and other proteins in the extracellular matrix. The inhibition of these enzymes leads to a decrease in restenosis, which is the recurrence of artery narrowing after angioplasty or stent placement. Trans-4-hydroxy-L-proline methyl ester hydrochloride has been shown to be effective against chemokine receptors, including CCR5 receptor and chemokines such as TNFα. It also inhibits cytokine production by inhibiting signaling pathways that lead to inflammation and cell proliferation.

Chemical properties

• Molecular weight: 181.62 g/mol
• Formula: C₆H₁₁NO₃·HCl
• Color/Form: White/Off-White Solid