2'-Hydroxychalcone

CAS: 1214-47-7

Ref. 3D-FH71183

Product Information

• Name: 2'-Hydroxychalcone
• Synonyms: Benzylidene-(2-hydroxyacetophenone)1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one, (2E)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one, 1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one, 2'-Hydroxy Benzalacetophenone, 2-(3-Phenyl-2-propenoyl)phenol, 2-Hydroxybenzalacetophenone, 2-Hydroxychalcone, 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-phenyl-, 3-Phenyl-1-(2-hydroxyphenyl)-2-propen-1-one, Benzylidene(2-hydroxyacetophenone), Chalcone, 2′-hydroxy-, NSC 18939, Rvc 556, o-Cinnamoylphenol, o-Hydroxychalcone
• CAS: 1214-47-7

Description

2'-Hydroxychalcone is a fluorescent probe that has been shown to be effective in the detection of amines. It can be used as a cell factor to measure mitochondrial membrane potential by measuring the intramolecular hydrogen transfer from the hydroxyl group on 2-hydroxychalcone to an amine. The fluorescence intensity of 2'-hydroxychalcone increases with increasing mitochondrial membrane potential, which can be measured using a fluorimeter. This probe also reacts with proteins and fatty acids, leading to increased fluorescence intensity. 2'-Hydroxychalcone has biological activities that are similar to those of tnf-α (tumour necrosis factor alpha).

• Brand: Biosynth

Chemical properties

• Molecular weight: 224.25 g/mol
• Formula: C₁₅H₁₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C15H12O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-11,16H/b11-10+
• InChI key: InChIKey=AETKQQBRKSELEL-ZHACJKMWSA-N
• SMILES: O=C(/C=C/c1ccccc1)c1ccccc1O