Icatibant acetate

CAS: 138614-30-9

Ref. 3D-FI146277

Product Information

• Name: Icatibant acetate
• Brand: Biosynth
• Description: Icatibant is a 10 amino acid peptidomimetic of bradykinin and a selective antagonist to the bradykinin B2 receptor. Icabinant has been used for the treatment of attacks in patients with hereditary angioedema. Recent evidence has shown a link between dysregulated bradykinin‐mediated inflammation and acute respiratory distress syndrome (ARDS), a common complication in COVID-19 patients. Icatibant was proposed to inhibit excessive activation of the bradykinin B2 receptor during the SARS-CoV-2 infection, reducing the risk of ARDS.

Chemical properties

• Molecular weight: 1,304.52 g/mol
• Formula: C₅₉H₈₉N₁₉O₁₃S•(C₂H₄O₂)x
• Purity: Min. 98 Area-%
• Color/Form: Powder