Product Information
Name:Lomeguatrib
Brand:Biosynth
Description:Inhibitor and pseudosubstrate of DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT). It is used as a sensitizer for the treatment of advanced solid tumors, including prostate, colorectal and central nervous system malignancies. Lomeguatrib inhibits the repair mechanism of DNA damage induced by alkylating agents such as temozolomide, and therefore potentiates its anti-cancer effects.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:326.17 g/mol
Formula:C10H8BrN5OS
Purity:Min. 95%
Color/Form:Solid
InChI:InChI=1S/C10H8BrN5OS/c11-5-1-6(18-3-5)2-17-9-7-8(14-4-13-7)15-10(12)16-9/h1,3-4H,2H2,(H3,12,13,14,15,16)
InChI key:InChIKey=JUJPKFNFCWJBCX-UHFFFAOYSA-N
SMILES:Nc1nc(OCc2cc(Br)cs2)c2[nH]cnc2n1
Technical inquiry about: Lomeguatrib
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