Loureirin B

CAS: 119425-90-0

Ref. 3D-FL74520

Product Information

• Name: Loureirin B
• Synonyms: 1-Propanone,1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl), 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-1-propanone, 1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)propan-1-one, 1-Propanone, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-, 4′-Hydroxy-2,4,6-trimethoxydihydrochalcone, Lr-B, Propan-1-one, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-

Description

Loureirin B is a natural compound that belongs to the group of linear polymers. It has been shown to inhibit the activity of P-glycoprotein (P-gp), which is an ATP-dependent efflux pump that transports a wide variety of drugs and other xenobiotics out of cells. Loureirin B has been shown to inhibit the activity of P-gp in cell culture, and may have potential for use as a treatment for autoimmune diseases and other disorders whose pathogenesis is related to P-gp function. The biological properties of this compound are still being investigated, but it has been found to increase mitochondrial functions in cellular models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 316.35 g/mol
• Formula: C₁₈H₂₀O₅
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C18H20O5/c1-21-14-10-17(22-2)15(18(11-14)23-3)8-9-16(20)12-4-6-13(19)7-5-12/h4-7,10-11,19H,8-9H2,1-3H3
• InChI key: InChIKey=ZPFRAPVRYLGYEC-UHFFFAOYSA-N
• SMILES: COc1cc(OC)c(CCC(=O)c2ccc(O)cc2)c(OC)c1