Methotrexate disodium

CAS: 7413-34-5

Ref. 3D-FM148819

Product Information

• Name: Methotrexate disodium
• Synonyms: <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, disodium salt, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, sodium salt (1:2), Amethopterin sodium, Disodium 2-[(4-{[(2,4-Diaminopteridin-6-Yl)Methyl](Methyl)Amino}Benzoyl)Amino]Pentanedioate, Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, disodium salt, <span class="text-smallcaps">L</span>-(+)-, Methotrexate Lederle, Metoart, Metotrexato Lederle, Sodium methotrexate, disodium N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamate, Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, disodium salt, L-(+)-, L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, sodium salt (1:2), L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, disodium salt

Description

Methotrexate is a drug that suppresses the immune system by inhibiting the production of white blood cells. It is used in the treatment of a number of diseases, including some cancers and autoimmune diseases such as rheumatoid arthritis and psoriasis. Methotrexate is metabolized to its active form, methotrexate, by an enzyme called dihydrofolate reductase (DHFR). The DHFR inhibitor activity of methotrexate blocks the synthesis of folate-dependent enzymes and prevents DNA synthesis in rapidly dividing cells. Methotrexate has been used in combination with other drugs to treat cancer. Methotrexate has also been shown to have antifungal properties against opportunistic fungal infections.

• Brand: Biosynth

Chemical properties

• Molecular weight: 498.4 g/mol
• Formula: C₂₀H₂₀N₈Na₂O₅
• Purity: Min. 95%
• Color/Form: Powder