2-Methoxyphenothiazine

CAS: 1771-18-2

Ref. 3D-FM70658

Product Information

• Name: 2-Methoxyphenothiazine
• Synonyms: 2-Methoxy-10H-phenothiazineMethyl phenothiazin-2-yl etherNSC 72107
• Brand: Biosynth
• Description: 2-Methoxyphenothiazine is an antihistamine drug used to treat allergy symptoms. It is available as a liquid formulation for adults and children over the age of 12 years. The pharmacokinetic properties of 2-methoxyphenothiazine have been studied in three clinical trials. In one study, the terminal half-life was found to be around 5 hours in both healthy subjects and patients with allergic rhinitis. In another study, 2-methoxyphenothiazine was administered intravenously to healthy subjects at two different doses. After administration, 2-methoxyphenothiazine plasma concentrations were measured using high performance liquid chromatography (HPLC). The bioavailability of 2-methoxyphenothiazine was found to be dose proportional following intravenous administration. 2-Methoxyphenothiazine is metabolized by hydrolysis of its ester group by esterases or glucuron

Chemical properties

• Molecular weight: 229.3 g/mol
• Formula: C₁₃H₁₁NOS
• Purity: 90%
• Color/Form: Powder
• InChI: InChI=1S/C13H11NOS/c1-15-9-6-7-13-11(8-9)14-10-4-2-3-5-12(10)16-13/h2-8,14H,1H3
• InChI key: InChIKey=DLYKFPHPBCTAKD-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)Nc1ccccc1S2