CAS 1771-18-2

2-Methoxy-10H-phenothiazine

Description:

2-Methoxy-10H-phenothiazine, with the CAS number 1771-18-2, is a chemical compound belonging to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound features a methoxy group (-OCH3) at the second position of the phenothiazine ring, influencing its chemical reactivity and solubility. It is typically a solid at room temperature and may exhibit a pale yellow to light brown color. 2-Methoxy-10H-phenothiazine is known for its potential applications in pharmaceuticals, particularly as an antipsychotic or antiemetic agent, due to its ability to interact with neurotransmitter systems. The compound's properties include moderate lipophilicity, which aids in its bioavailability, and it may undergo various chemical reactions, such as oxidation or substitution, under specific conditions. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance. Overall, 2-Methoxy-10H-phenothiazine is a significant compound in medicinal chemistry with diverse applications.

Formula: C₁₃H₁₁NOS

InChI: InChI=1/C13H11NOS/c1-15-9-6-7-13-11(8-9)14-10-4-2-3-5-12(10)16-13/h2-8,14H,1H3

InChI key: InChIKey=DLYKFPHPBCTAKD-UHFFFAOYSA-N

SMILES: O(C)C=1C=C2C(SC=3C(N2)=CC=CC3)=CC1

Synonyms:

• 10H-Phenothiazine, 2-Methoxy-
• 2-Methoxy-10H-phenothiazine
• 2-Methoxy-phenothiazine
• 2-MethoxyPhenthiazine
• MethoxyPhenoThiazine
• Methyl phenothiazin-2-yl ether
• NSC 72107
• Phenothiazine, 2-methoxy-
• 2-Methoxyphenothiazine
• 2-METHOXYPHENOTHIAZINE 95+%

2-Methoxyphenothiazine

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Purity: >98.0%(HPLC)

Color and Shape: White to Light gray to Light yellow powder to crystal

Molecular weight: 229.30

Ref: 3B-M0822

2-Methoxyphenothiazine

CAS: 1771-18-2

2-Methoxy Phenothiazine is light yellow or light gray solid.

Formula: C₁₃H₁₁NOS

Purity: 99.28%

Color and Shape: Solid

Molecular weight: 229.298

Ref: TM-T0642

2-Methoxy-10H-phenothiazine

CAS: 1771-18-2

2-Methoxy-10H-phenothiazine

Formula: C₁₃H₁₁NOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 229.29753

Ref: 54-OR52313

2-Methoxyphenothiazine

CAS: 1771-18-2

2-Methoxyphenothiazine

Formula: C₁₃H₁₁NOS

Purity: ≥98%

Molecular weight: 229.3

Ref: 54-BUP17846

Levomepromazine EP Impurity A

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Color and Shape: Off-White Solid

Molecular weight: 229.30

Ref: 4Z-L-104008

2-Methoxyphenothiazine

Controlled Product

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Color and Shape: Neat

Molecular weight: 229.3

Ref: 86-MM0019.02

2-Methoxy-10H-phenothiazine

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 229.2975

Ref: IN-DA002543

2-Methoxy Phenothiazine

CAS: 1771-18-2

Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.
References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)

Formula: C₁₃H₁₁NOS

Color and Shape: Neat

Molecular weight: 229.3

Ref: TR-M265330

2-Methoxyphenothiazine

CAS: 1771-18-2

2-Methoxyphenothiazine is an antihistamine drug used to treat allergy symptoms. It is available as a liquid formulation for adults and children over the age of 12 years. The pharmacokinetic properties of 2-methoxyphenothiazine have been studied in three clinical trials. In one study, the terminal half-life was found to be around 5 hours in both healthy subjects and patients with allergic rhinitis. In another study, 2-methoxyphenothiazine was administered intravenously to healthy subjects at two different doses. After administration, 2-methoxyphenothiazine plasma concentrations were measured using high performance liquid chromatography (HPLC). The bioavailability of 2-methoxyphenothiazine was found to be dose proportional following intravenous administration. 2-Methoxyphenothiazine is metabolized by hydrolysis of its ester group by esterases or glucuron

Formula: C₁₃H₁₁NOS

Purity: 90%

Color and Shape: Powder

Molecular weight: 229.3 g/mol

Ref: 3D-FM70658

2-Methoxyphenothiazine

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Molecular weight: 229.3

Ref: BE-RMCL074007

2-Methoxyphenothiazine

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Purity: 95%

Color and Shape: Solid

Molecular weight: 229.3

Ref: 10-F154300

2-Methoxyphenothiazine

CAS: 1771-18-2

2-Methoxyphenothiazine

Formula: C₁₃H₁₁NOS

Purity: 96%

Molecular weight: 229.3

Ref: IN-DG14604

2-Methoxy Phenothiazine-D3

Controlled Product

CAS: 1771-18-2

Applications 2-Methoxy Phenothiazine-D3 is an intermediate in the synthesis of rac Methotrimeprazine-d3 Hydrochloride (M260786), which is an analgesic.
References Viaud, et al.: J. Pharm. and Pharmacol., 6, 361 (1954),

Formula: C₁₃D₃H₈NOS

Color and Shape: Neat

Molecular weight: 232.316

Ref: TR-M265332

Levomepromazine EP Impurity A

CAS: 1771-18-2

Formula: C₁₃H₁₁NOS

Molecular weight: 229.3

Ref: ST-EA-CP-L72001