Product Information
- (2E)-3-(4-nitrophenyl)-1-phenylprop-2-en-1-one
- (4-Nitrobenzylidene)acetophenone
- 1-(4-Nitrophenyl)-3-oxo-3-phenylpropene
- 1-Phenyl-3-(4-nitrophenyl)-2-propen-1-one
- 1-Phenyl-3-(4-nitrophenyl)-2-propenone
- 2-Propen-1-one, 3-(4-nitrophenyl)-1-phenyl-
- 3-(4-Nitrophenyl)-1-Phenylprop-2-En-1-One
- 3-(4-Nitrophenyl)-1-phenyl-2-propen-1-one
- 3-(p-Nitrophenyl)-1-phenyl-2-propen-1-one
- 4-Nitrostyryl phenyl ketone
- See more synonyms
- Chalcone, 4-nitro-
- NSC 3383
- NSC 636936
- p-Nitrobenzylideneacetophenone
- p-Nitrochalcone
- p-Nitrostyryl phenyl ketone
4-Nitrochalcone is a natural compound that has been found to be effective in the treatment of leukemia. It is synthesized from 2-hydroxybenzoic acid and nitric acid. 4-Nitrochalcone reacts with maleic anhydride to form a mixture of 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid. This reaction occurs in a reaction vessel at 220 degrees Celsius. The mixed product is then hydrolyzed by hydrochloric acid to release the 3,4-dihydroxybenzoic acid and 3,5-dihydroxybenzoic acid. The nitro group on the 3,5-dihydroxylbenzoic acid leaves as nitrous oxide gas during this process. The 3,5-dihydroxylbenzoic acids are potent inhibitors of mitochondrial membrane potential and can thus inhibit cell respiration. Nitro groups
Chemical properties
Technical inquiry about: 3D-FN158931 4-Nitrochalcone
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