Naloxone hydrochloride

CAS: 357-08-4

Ref. 3D-FN26128

Product Information

• Name: Naloxone hydrochloride
• Synonyms: (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride17-Allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one hydroch lorideNalone, (-)-N-Allyl-14-hydroxynordihydromorphinone hydrochloride, (5Alpha)-3,14-Dihydroxy-17-Prop-2-En-1-Yl-4,5-Epoxymorphinan-6-One Hydrochloride, En 1530, En 15304, Morphinan-6-one, 17-allyl-4,5α-epoxy-3,14-dihydroxy-, hydrochloride, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-, hydrochloride (1:1), (5α)-, Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, hydrochloride, (5α)-, N-Allyldihydro-14-hydroxynormorphinone hydrochloride, Nalone, Nalonee, Naloxone HCl, Narcan, Narcanti, Narcoxone, Nih 7890, Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, hydrochloride, l-Naloxone hydrochloride

Description

Naloxone hydrochloride is a competitive antagonist at mu-, delta- and kappa-opioid receptors. Naloxone binding to receptors blocks the effects of opioids such as morphine, heroin, or oxycodone. Naloxone has been shown to be effective in treating acute overdoses of these drugs and reversing the depression of respiratory function that accompanies opioid overdose. It is also used to alleviate withdrawal symptoms and in the treatment of neonatal abstinence syndrome (NAS). NAS is a condition that occurs when infants are exposed to addictive levels of opioids in utero and go through withdrawal after birth.

• Brand: Biosynth

Chemical properties

• Molecular weight: 363.84 g/mol
• Formula: C₁₉H₂₁NO₄•HCl
• Purity: (%) Min. 95%
• Color/Form: Powder