Nedaplatin

CAS: 95734-82-0

Ref. 3D-FN65098

Product Information

• Name: Nedaplatin
• Synonyms: (Glycolato-O,O')Diammineplatinum(Ii), (SP-4-3)-Diammine[2-(hydroxy-κO)acetato(2-)-κO]platinum, 254-S, Acetic acid, hydroxy-, platinum complex, Aqupla, Cis-Diammine(Glycolato)Platinum(Ii), Diammine(Glycolato)Platinum(Ii) Nedaplatin Nsc 375101D, NSC 375101, Nedaplait, O(Sup 2))- Diammine(Hydroxyacetato(2-)-O(Sup 1 (Sp-4-3)-Platinu (Glycolato-O,O')Diammineplatinum(Ii) 254-S Cis-, O(Sup2))-Diammine(Hydroxyacetato(2-)-O(Sup1(Sp-4-3)-Platinu, Platinum(2+) Azanide - Hydroxyacetic Acid (1:2:1), Platinum, diammine[(hydroxy-κO)acetato(2-)-κO]-, (SP-4-3)-, Platinum, diammine[2-(hydroxy-κO)acetato(2-)-κO]-, (SP-4-3)-, Platinum, diammine[hydroxyacetato(2-)-O¹,O²]-, (SP-4-3)-, S 254, diamino[(hydroxy-kappaO)acetato(2-)-kappaO]platinum, Platinum, diammine[hydroxyacetato(2-)-O1,O2]-, (SP-4-3)-

Description

Nedaplatin is a platinum-based anti-cancer drug that has been reported to have significant cytotoxicity against human osteosarcoma cells. It is used in chemotherapy as a radiosensitizer. Nedaplatin can be used to treat cancers that are unresponsive to cisplatin, such as non-small cell lung cancer, ovarian cancer, and breast cancer. Nedaplatin is administered intravenously and has acute toxicities that include nephrotoxicity, neurotoxicity, and ototoxicity. This drug is an anti-cancer compound that has been shown to inhibit the proliferation of cells by binding with DNA at the site of DNA damage and inhibiting DNA repair. The polymer coating on nedaplatin reduces its toxicity by preventing it from entering cells through passive diffusion.

• Brand: Biosynth

Chemical properties

• Molecular weight: 303.18 g/mol
• Formula: C₂H₂O₃Pt·2H₃N
• Purity: Min. 95%
• Color/Form: Powder