Product Information
Name:Oridonin
Synonyms:
- Isodonol7a,20-Epoxy-1a,6b,7,14-tetrahydroxy-Kaur-16-en-15-one
Brand:Biosynth
Description:A diterpenoid from Chinese medicinal plant Rabdosia rubescens with anti-inflammatory activity. It is a potent inhibitor of NF-κB and MAPK activation and suppresses the release of proinflammatory cytokines. It is also a covalent inhibitor of NLRP3, a sensor component of NLRP3 inflammasome. In a rodent model for cerebral amyloidosis, oridonin effectively prevented neuroinflammation and Alzheimer’s disease-associated neuropathological changes. It reduced numbers of amyloid-β plaques in mice brain and reversed behaviour and social impairment.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:364.44 g/mol
Formula:C20H28O6
Purity:Min. 98 Area-%
Color/Form:White Powder
Technical inquiry about: Oridonin
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