Product Information
- N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy)propyl]-glycine
A selective inhibitor of glial glycine transporter type 1 (GlyT-1b). It has no considerable affinity for noradrenaline, dopamine, serotonin and GABA receptors. Increases amplitude of electronically evoked NMDA receptor-mediated glutamatergic excitatory postsynaptic current (eEPSCs). This raises glycine levels in spinal cord slides and extends the duration of current at glycinergic synapses.
Chemical properties
Technical inquiry about: 3D-FO100627 Org 24598
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