Ornidazole

CAS: 16773-42-5

Ref. 3D-FO26585

Product Information

• Name: Ornidazole
• Synonyms: a-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitro imidazole, (±)-Tiberal, 1(3-Chloro-2-Hydroxypropyl)-2-Methyl-5-Nitro Imidazole, 1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole, 1-Chloro-3-(2-methyl-5-nitro-imidazol-1-yl)-propan-2-ol, 1-Chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol, 1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol, 1H-Imidazole-1-ethanol, α-(chloromethyl)-2-methyl-5-nitro-, Dazolic, Imidazole-1-ethanol, α-(chloromethyl)-2-methyl-5-nitro-, Madelen, NSC 95075, Ornidal, Ornidone, Ornilox, Ornisid, Ornitop, Ro 7-0207, alpha-(chloromethyl)-2-methyl-5-nitro-1H-Imidazole-1-ethanol, α-(Chloromethyl)-2-methyl-5-nitro-1-imidazoleethanol, α-(Chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol

Description

Ornidazole is a drug that belongs to the group of antimicrobial agents. It is used in the treatment of infections caused by anaerobic bacteria, such as Clostridium difficile, and protozoa such as Giardia lamblia. Ornidazole inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ornidazole also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 219.63 g/mol
• Formula: C₇H₁₀ClN₃O₃
• Purity: Min. 98 Area-%
• Color/Form: White Slightly Yellow Powder