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CAS 16773-42-5

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Ornidazole

Description:
Ornidazole is an antiprotozoal and antibacterial agent belonging to the nitroimidazole class of compounds. It is primarily used in the treatment of various infections, particularly those caused by anaerobic bacteria and protozoa, such as amoebiasis and giardiasis. The chemical structure of ornidazole features a nitro group attached to an imidazole ring, which is crucial for its biological activity. It is typically administered orally and is known for its good absorption and distribution in the body. Ornidazole exhibits a relatively long half-life, allowing for once-daily dosing in many cases. The substance is generally well-tolerated, although side effects may include gastrointestinal disturbances, headache, and dizziness. Its mechanism of action involves the reduction of the nitro group, leading to the formation of reactive intermediates that damage microbial DNA. Ornidazole is also noted for its effectiveness against certain strains of bacteria that are resistant to other antibiotics, making it a valuable option in clinical settings.
Formula:C7H10ClN3O3
InChI:InChI=1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3
InChI key:InChIKey=IPWKIXLWTCNBKN-UHFFFAOYSA-N
SMILES:C(C(CCl)O)N1C(N(=O)=O)=CN=C1C
Synonyms:
  • (±)-Tiberal
  • 1(3-Chloro-2-Hydroxypropyl)-2-Methyl-5-Nitro Imidazole
  • 1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
  • 1-Chloro-3-(2-methyl-5-nitro-imidazol-1-yl)-propan-2-ol
  • 1-Chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol
  • 1-chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
  • 1H-Imidazole-1-ethanol, α-(chloromethyl)-2-methyl-5-nitro-
  • Dazolic
  • Imidazole-1-ethanol, α-(chloromethyl)-2-methyl-5-nitro-
  • Madelen
  • See more synonyms
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