Lorlatinib
CAS:
Ref. 3D-FP104236
1g
1,016.00€
50mg
187.00€
100mg
241.00€
250mg
469.00€
500mg
761.00€
Product Information
Name:Lorlatinib
Synonyms:
- (10R)-7-Amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetrad ecine-3-carbonitrilePF 06463922
Brand:Biosynth
Description:Brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK) and proto-oncogene kinase ROS1. It is a reversible ATP-competitor, interacting with P-loop (L1122, G1123, V1130) and K1150 residue of ALK tyrosine kinase. It has major implications in the treatment of non-small cell lung cancer (NSCLC). The compound is used for resensitization of drug resistant, ALK-mutated cancers to crizotinib chemotherapy and was shown to trigger the regression of EML40ALK-driven brain metastases.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:406.41 g/mol
Formula:C21H19FN6O2
Purity:Min. 95%
Technical inquiry about: Lorlatinib
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.