Plitidepsin

CAS: 137219-37-5

Ref. 3D-FP178389

Product Information

• Name: Plitidepsin
• Brand: Biosynth
• Description: Plitidepsin is a natural product first isolated from a marine tunicate Aplidium albicans. Plitidepsin has anti-cancer properties as it can induce cell cycle arrest, apoptosis and was also reported to have anti-angiogenic properties. Plitidepsin possesses a potent antiviral activity in vitro against SARS-CoV-2 with IC90 = 0.88nM, which results to be 27.5-fold more potent than the RdRp inhibitor remdesivir. Plitidepsin targets the host protein synthesis factor, eEF1A, and was shown to greatly reduce the subgenomic RNA expression during viral infection.

Chemical properties

• Molecular weight: 1,110.34 g/mol
• Formula: C₅₇H₈₇N₇O₁₅
• Purity: Min. 95%
• Color/Form: Powder