Product Information
Name:Palonosetron N-oxide
Synonyms:
- (3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one
Brand:Biosynth
Description:Palonosetron N-oxide is a n-oxide of palonosetron that was synthesized by reacting the drug with nitric acid. It is an impurity in the synthesis of palonosetron, which is used to treat severe nausea and vomiting. The solvents used in this reaction are dimethylsulfoxide (DMSO) and water. The parameters involved were temperature, time, and concentration. Impurities were detected using thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), and mass spectrometry (MS). The chemical structure of Palonosetron N-oxide is shown below: The equation for the synthesis of Palonosetron N-oxide is as follows: 2PALONOSETRON + HNO3 → PN-OXIDE + 2H2O+NOx
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:312.41 g/mol
Formula:C19H24N2O2
Purity:Min. 95%
Technical inquiry about: Palonosetron N-oxide
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