Pentamidine

CAS: 100-33-4

Ref. 3D-FP26808

Product Information

• Name: Pentamidine
• Synonyms: 4,4'-[1,5-Pentanediylbis(oxy)]bis-benzenecarboximidamide4,4'-Diamidino-.alpha.,.omega.-diphenoxypentaneMP 601205, 2-Hydroxyethanesulfonic Acid - 4,4'-[Pentane-1,5-Diylbis(Oxy)]Dibenzenecarboximidamide (2:1), 4,4'-(Pentamethylenedioxy)dibenzamidine, 4,4'-Diamidino-α,ω-diphenoxypentane, 4,4'-[Pentane-1,5-Diylbis(Oxy)]Dibenzenecarboximidamide, 4,4-Pentamethylenedioxydibenzamidine, 4,4′-[1,5-Pentanediylbis(oxy)]bis[benzenecarboximidamide], Benzamidine, 4,4'-(pentamethylenedioxy)di-, Benzenecarboximidamide, 4,4'-[1,5-pentanediylbis(oxy)]bis-, Mp 601205, Nsc 9921, Pentamidin, Pentamidina, p,p'-(Pentamethylenedioxy)dibenzamidine

Description

Pentamidine is a nonsteroidal anti-inflammatory drug that inhibits the polymerase chain reaction. Pentamidine has been shown to inhibit the growth of Leishmania, a protozoan parasite that causes leishmaniasis. It binds to DNA and alters its structure, which prevents transcription and replication. This drug also has a low toxicity and side effect profile, making it an attractive candidate for development as an anti-leishmanial agent.

• Brand: Biosynth

Chemical properties

• Molecular weight: 340.42 g/mol
• Formula: C₁₉H₂₄N₄O₂
• Purity: Min. 95 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)
• InChI key: InChIKey=XDRYMKDFEDOLFX-UHFFFAOYSA-N
• SMILES: N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1