Phenylephrine hydrochloride

CAS: 61-76-7

Ref. 3D-FP26956

Product Information

• Name: Phenylephrine hydrochloride
• Synonyms: 3-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrochloride (1:1), (-)-α-Hydroxy-β-(methylamino)ethyl-α-(3-hydroxybenzene)hydrochloride, (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride, (R)-3-Hydroxy-[α-(methylamino)methyl]benzene methanol hydrochloride, (R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride, (R)-Phenylephrine hydrochloride, 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride, Adrianol, Ak-Dilate, Ak-Nefrin, Alcon Efrin, Almefrin, Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1), (αR)-, Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (R)-, Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (αR)-, Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (-)-, D-(-)-Phenylephrinehydrochloride, Decadron, Fenilefrina, Clorhidrato, Irifrin, Isophrin, Isophrin hydrochloride, Levophenylephrine hydrochloride, Lexatol, M-Sympatol, Meta-Sympatol, Meta-Synephrine hydrochloride, Metaoxedrine chloride, Metaoxedrine hydrochloride, Mydfrin, Neo-Synephrine hydrochloride, Neo-Synesin 1, Neophryn, Neosinesine, Nostril, Oftalfrine, Phenylephrine HCL, Phenylephrine Hydrochloride, Phenylephrine, chlorhydrate, Phenylephrinhydrochlorid, Prefrin, Pyracort D, R-(-)-m-Synephrine hydrochloride, Sucraphen, Synasal, l-1-(m-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, l-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride, l-α-Hydroxy-β-methylamino-3-hydroxy-1-ethylbenzene hydrochloride

Description

(R)-Phenylephrine hydrochloride is a non selective alpha adrenergic agonist that can be used as a bronchodilator or vasopressor. Some research studies in rat liver microsomes has shown that (R)-phenylephrine can be converted to phenylephrine by alcohol dehydrogenase at a rate constant of around 1.8x103 M-1s-1 at 37°C. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle and increase blood pressure by stimulating alpha-adrenergic receptors in the body. This drug is also used in chromatography for control analysis and detection of adulteration with other compounds, such as norepinephrine, with the help of benzalkonium chloride.In ophthalmology, phenylephrine hydrochloride formulations are used for the treatment of eye disorders such as myopia, hypermetropia and astigmatism. It increases the outflow of aqueous humour from the eye by acting on alpha receptors in the ciliary body, and seems to be effective in controlling symptoms of allergic rhinitis and chronic urticaria.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.67 g/mol
• Formula: C₉H₁₄NO₂Cl
• Purity: Min. 98 Area-%
• Color/Form: Powder