2-Phenyl-1,3-indandione

CAS: 83-12-5

Ref. 3D-FP63877

Product Information

• Name: 2-Phenyl-1,3-indandione
• Synonyms: Phenindione
• Brand: Biosynth
• Description: 2-Phenyl-1,3-indandione is a coumarin derivative that is used as an anti-inflammatory drug. It inhibits the release of arachidonic acid from phospholipids in the cell membrane and consequently inhibits the formation of prostaglandins. The drug has been shown to inhibit light-induced tumor promotion in mice with cervical cancer, which may be due to its ability to inhibit the activity of oxidative enzymes such as cytochrome P450. 2-Phenyl-1,3-indandione also inhibits sodium-dependent glucose transport and energy metabolism by binding to potassium channels. This drug also has immunosuppressive effects on lymphocyte transformation and autoimmune diseases through hydrogen bonding interactions with protein molecules.

Chemical properties

• Molecular weight: 222.24 g/mol
• Formula: C₁₅H₁₀O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H
• InChI key: InChIKey=NFBAXHOPROOJAW-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2C(=O)C1c1ccccc1