2-Phenyl-1,3-indandione

CAS: 83-12-5

Ref. 3D-FP63877

Product Information

• Name: 2-Phenyl-1,3-indandione
• Synonyms: Phenindione, 1,3-Indandione, 2-phenyl-, 1H-Indene-1,3(2H)-dione, 2-phenyl-, 2-Phenyl-1,3-diketohydrindene, 2-Phenyl-1,3-indanedione, 2-Phenyl-1H-inden-1,3(2H)-dione, 2-Phenyl-1H-indene-1,3(2H)-dione, 2-Phenyl-2,3-dihydro-1H-indene-1,3-dione, 2-Phenylindandione, 2-Phenylindene-1,3-dione, 3-hydroxy-2-phenyl-1H-inden-1-one, Athrombon, Bindan, Cronodione, Danedion, Danilon, Danilone, Diadilan, Dindevan, Dineval, Diophindane, Emandion, Emandione, Fenhydren, Fenilin, Fenindion, Fenindiona, Hedulin, Hemolidione, Indema, Indion, Indon, Nsc 41693, PID, Phenhydren, Phenillin, Phenindion, Phenylen, Phenylin, Phenylindione, Pindione, Rectadione, Theradione, Thrombasal, Tromazal, Trombol

Description

2-Phenyl-1,3-indandione is a coumarin derivative that is used as an anti-inflammatory drug. It inhibits the release of arachidonic acid from phospholipids in the cell membrane and consequently inhibits the formation of prostaglandins. The drug has been shown to inhibit light-induced tumor promotion in mice with cervical cancer, which may be due to its ability to inhibit the activity of oxidative enzymes such as cytochrome P450. 2-Phenyl-1,3-indandione also inhibits sodium-dependent glucose transport and energy metabolism by binding to potassium channels. This drug also has immunosuppressive effects on lymphocyte transformation and autoimmune diseases through hydrogen bonding interactions with protein molecules.

• Brand: Biosynth

Chemical properties

• Molecular weight: 222.24 g/mol
• Formula: C₁₅H₁₀O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H
• InChI key: InChIKey=NFBAXHOPROOJAW-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2C(=O)C1c1ccccc1