Orelabrutinib
CAS: 1655504-04-3
Ref. 3D-FRC50404
| 5mg | 187.00 € | ||
| 10mg | 281.00 € | ||
| 25mg | 470.00 € | ||
| 50mg | 704.00 € | ||
| 100mg | 1,053.00 € |
Product Information
Orelabrutinib is a potent inhibitor of Bruton's tyrosine kinase (BTK). It has been shown to inhibit the BTK enzyme in both human and mouse cells, which prevents activation of the B-cell receptor and inhibits immunoglobulin production. Orelabrutinib is also a 5-HT1A agonist and has been shown to have anti-cancer effects on drug-resistant acute lymphocytic leukemia. The drug binds to the active site of BTK as a covalent inhibitor, resulting in its inhibition. Orelabrutinib also acts as an antagonist at serotonin receptors 5-HT1A, leading to its potential therapeutic effects in autoimmune diseases.
Chemical properties
Technical inquiry about: 3D-FRC50404 Orelabrutinib
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