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SAG

CAS: 912545-86-9

Ref. 3D-FS27779

1g		1,618.00 €
2g		2,442.00 €
10mg		174.00 €
50mg		479.00 €
500mg		1,216.00 €

Estimated delivery in United States, on Tuesday 28 May 2024

Safety Data Sheet

Product Information

Name:

SAG

Synonyms:

3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide

CAS:

912545-86-9

Description:

Smoothened agonist and activator of the Hedgehog signalling pathway with EC50 of 3 nM. SAG binds to the Smoothened heptahelical bundle and antagonises effects of the Smoothened antagonist cyclopamine. In previous studies, SAG activated neurogenesis and neuronal survival in cell and animal models as well as improved cell differentiation of human induced pluripotent cells into the neuronal lineage.

Brand:

Biosynth

Long term storage:

Notes:

Chemical properties

Molecular weight:

490.06 g/mol

Formula:

C₂₈H₂₈ClN₃OS

Purity:

Min. 95%

Color/Form:

White Powder

InChI:

InChI=1S/C28H28ClN3OS/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20/h2-8,13-17,22-23,30H,9-12,18H2,1H3

InChI key:

InChIKey=VFSUUTYAEQOIMW-UHFFFAOYSA-N

SMILES:

CNC1CCC(N(Cc2cccc(-c3ccncc3)c2)C(=O)c2sc3ccccc3c2Cl)CC1

MDL:

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Merck:

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Hazard Info

UN Number:

EQ:

Class:

H Statements:

P Statements:

Forbidden to fly:

Hazard Info:

Packing Group:

LQ:

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SAG