Selumetinib
CAS: 606143-52-6
Ref. 3D-FS27812
| 10mg | 136.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 206.00 € | ||
| 250mg | 386.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Product Information
Name:
Selumetinib
Synonyms:
- 5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
- 1H-Benzimidazole-6-carboxamide, 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-
- 5-(4-Bromo-2-chlorophenylamino)-4-fluoro-1-methyl-1H-benzimidazole-6-carbohydroxamic acid 2-hydroxyethyl ester
- 6-(4-Bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
- Arry-142886
- Azd 6244
- Azd-6224
- Azd6244
- G 00039805
- Koselugo
- See more synonyms
- NSC 741O78
- Zd-6244
Description:
Potent and selective MAP/ERK kinase 1/2 inhibitor. Reduces growth of tumor cells with B-Raf and Ras mutations. Tumor regression observed after chronic treatment in in vivo xenograft models. Enhances anti-tumor effect in combination with irinotecan or docetaxel.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
457.68 g/mol
Formula:
C17H15BrClFN4O3
Purity:
Min. 98 Area-%
Color/Form:
White Powder
InChI:
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChI key:
InChIKey=CYOHGALHFOKKQC-UHFFFAOYSA-N
SMILES:
Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(C(=O)NOCCO)cc21
MDL:
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HS code:
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