Product Information
Name:Selumetinib
Synonyms:
- 5-[(4-Bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide
Brand:Biosynth
Description:Potent and selective MAP/ERK kinase 1/2 inhibitor. Reduces growth of tumor cells with B-Raf and Ras mutations. Tumor regression observed after chronic treatment in in vivo xenograft models. Enhances anti-tumor effect in combination with irinotecan or docetaxel.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:457.68 g/mol
Formula:C17H15BrClFN4O3
Purity:Min. 98 Area-%
Color/Form:White Powder
InChI:InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChI key:InChIKey=CYOHGALHFOKKQC-UHFFFAOYSA-N
SMILES:Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(C(=O)NOCCO)cc21
Technical inquiry about: Selumetinib
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