Sodium stibogluconate

CAS: 16037-91-5

Ref. 3D-FS76282

Product Information

• Name: Sodium stibogluconate
• Synonyms: (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, 1,3,2-Dioxantimonane, <span class="text-smallcaps">D</span>-gluconic acid deriv., 1,3,2-Dioxastibinane, <span class="text-smallcaps">D</span>-gluconic acid deriv., <span class="text-smallcaps">D</span>-Gluconic acid, 2,4:2′,4′-O-(oxydistibylidyne)bis-, Sb,Sb′-dioxide, trisodium salt, nonahydrate, <span class="text-smallcaps">D</span>-Gluconic acid, 2,4:2′,4′-O-(oxydistibylidyne)bis-, sodium salt, hydrate (1:3:9), <span class="text-smallcaps">D</span>-Gluconic acid, 2,4:2′,4′-O-[oxybis(oxidostibylidyne)]bis-, trisodium salt, nonahydrate, <span class="text-smallcaps">D</span>-Gluconic acid, cyclic ester with antimonic acid (H₈Sb₂O₉) (2:1), trisodium salt, nonahydrate, Antimony (V) derivative of sodium gluconate, Antimony sodium gluconate, D-Gluconic acid, 2,4:2',4'-O-(oxydistibylidyne)bis-, Sb,Sb'-dioxide, trisodium salt, nonahydrate, D-Gluconic acid, cyclic ester with antimonic acid (H8Sb2O9) (2:1), trisodium salt, nonahydrate, Dioxodistiboxane - Hexonic Acid (1:2), Estibogluconato sodico, Estibogluconato sodico [INN-Spanish], Estibogluconato sodico [Spanish], Hexonic Acid, Antimony Sodium Salt (2:2:3), Dodecahydrate, Myostibin, Natrii stibogluconas, Natrii stibogluconas [INN-Latin], Nonahydrate, Oxo-Oxostibanyloxy-Stibane, Pentostam, Sodium stibogluconate [INN:BAN:DCF], Solustibosan, Solustin, Solusurmin, Solyusurmin, Stibanate, Stibanose, Stibatin, Stibinol, Stibogluconate de sodium, Stibogluconate de sodium [INN-French], Stibogluconate sodique, Stibogluconate sodium, Trinatrium bis(gluconato(3)-O2,O3,O4)hydroxooxido-oxy-bis-antimonat(V), Trisodium, Unii-V083S0159D

Description

Sodium stibogluconate is a drug that has been widely used in the treatment of leishmaniasis. It is administered as an intramuscular injection or intravenous infusion, depending on the severity of the infection. The drug targets the parasite by inhibiting its DNA topoisomerase, which disrupts DNA replication and transcription. Clinical data have shown that this drug is effective against infantum and other strains of leishmania.

Sodium stibogluconate is used to treat cutaneous leishmaniasis, which are skin lesions caused by Leishmania parasites. This drug can be administered as an intramuscular injection or intravenous infusion depending on the severity of the infection. Sodium stibogluconate works by targeting Leishmania parasites by inhibiting their DNA topoisomerase, which disrupts DNA replication and transcription. Clinical data has shown that this drug is effective against infantum and other strains of leishmania.

• Brand: Biosynth

Chemical properties

• Molecular weight: 910.9 g/mol
• Formula: C₁₂H₂₀O₁₇Sb₂•(Na)₃•(H₂O)₉
• Purity: Min. 95%
• Color/Form: Powder