trans-Tranexamic acid

CAS: 1197-18-8

Ref. 3D-FT163756

Product Information

• Name: trans-Tranexamic acid
• Synonyms: Amchafibrintrans-p-(Aminomethyl)cyclohexanecarboxylic acid, 4-(Aminomethyl)Cyclohexanecarboxylic Acid, 4-trans-Aminomethylcyclohexanecarboxylic acid, Acide Tranexamique, Acido Tranexamico, Amca, Amcha, Amchafibrin, Amikapron, Amstat, Anvitoff, Bay 3517, Cl 65336, Cyclocapron, Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-, Cyclokapron, Cyklokapron, Dv 79, Exacyl, Haematrix, Haku, Lysteda, Tamcha, Tranexaminsaure, Tranol, Trans-4-aminomethylcyclohexanecarboxylic acid, Trans-Cyclohexanecarboxylic Acid, Transamin, Transamin G, Transamin S, Transcam, Ugurol, Xamig, Xed, Zataranax, t-AMCHA, trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid, trans-4-(Aminomethyl)cyclohexane carboxylic acid, trans-4-(Aminomethyl)cyclohexanecarboxylic acid, trans-4-Aminomethylcyclohexane-1-carboxylate, trans-Amcha, trans-p-(Aminomethyl)cyclohexanecarboxylic acid

Description

Trans-tranexamic acid is a drug that has been used in cardiac surgery and to control blood loss during childbirth. It is also used to treat people with bowel disease who have heavy or prolonged bleeding. Trans-tranexamic acid works by inhibiting the activity of plasminogen activators, which are enzymes that break down fibrin clots. Tranexamic acid has been shown to be effective for treating people with severe sepsis and meningitis, although it does not appear to be effective for treating malaria. Trans-tranexamic acid binds to plasminogen activator inhibitor type 1 (PAI-1), preventing its activation and, therefore, preventing the breakdown of fibrin clots. Tranexamic acid also prevents the release of histamine from mast cells and basophils, which may contribute to its anti-inflammatory effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 157.21 g/mol
• Formula: C₈H₁₅NO₂
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)
• InChI key: InChIKey=GYDJEQRTZSCIOI-UHFFFAOYSA-N
• SMILES: NCC1CCC(C(=O)O)CC1